CRTC3 anticorps

N° du produit ABIN969068

L’anticorps Souris Monoclonal anti-CRTC3 a été validé pour WB, IHC, ELISA et ICC. Il convient pour détecter CRTC3 dans des échantillons de Humain et Singe. Il y a 2+ publications disponibles.

Aperçu rapide pour CRTC3 anticorps (ABIN969068)

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRTC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 5G9

Détail du produit anti-CRTC3 anticorps

Fonction: CRTC3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CRTC3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CRTC3 (ABIN969068)

Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).

Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: "A new type of MAML2 fusion in mucoepidermoid carcinoma." dans: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).

Détails sur CRTC3

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Autre désignation: CRTC3

Sujet: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

Poids moléculaire: 68 kDa

ID gène: 64784

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2