MDM4-binding Protein anticorps

N° du produit ABIN969282

Cet anticorps anti-MDM4-binding Protein est un anticorps Souris Monoclonal détectant MDM4-binding Protein dans ELISA, IHC et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour MDM4-binding Protein anticorps (ABIN969282)

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MDM4-binding Protein est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 2D10F4

Détail du produit anti-MDM4-binding Protein anticorps

Fonction: MDM4 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MDM4 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MDM4-binding Protein (ABIN969282)

Pan, Chen: "Modification of MDMX by sumoylation." dans: Biochemical and biophysical research communications, Vol. 332, Issue 3, pp. 702-9, (2005) (PubMed).

Wunderlich, Ghosh, Weghorst, Berberich: "MdmX represses E2F1 transactivation." dans: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 4, pp. 472-8, (2004) (PubMed).

Détails sur MDM4-binding Protein

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Autre désignation: MDM4

Sujet: MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.

Poids moléculaire: 55 kDa

ID gène: 4194

UniProt: O15151

Pathways: Cycle Cellulaire