NAMPT anticorps (AA 338-479)

N° du produit ABIN969344

Il existe 1 publication pour ce produit. L’anticorps anti-NAMPT Monoclonal Souris est utilisé pour la détection de NAMPT dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour NAMPT anticorps (AA 338-479) (ABIN969344)

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NAMPT est non-conjugé

Application: ELISA

Clone: 1D3A12

Détail du produit anti-NAMPT anticorps

Épitope: AA 338-479

Fonction: PBEF1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NAMPT (ABIN969344)

Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: "Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis." dans: European journal of immunology, Vol. 32, Issue 11, pp. 3225-34, (2003) (PubMed).

Détails sur NAMPT

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Autre désignation: PBEF1

Sujet: PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

UniProt: P43490