PPP1CA anticorps

N° du produit ABIN969360

Cet anticorps anti-PPP1CA est un anticorps Souris Monoclonal détectant PPP1CA dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour PPP1CA anticorps (ABIN969360)

Antigène: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPP1CA est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5E9

Détail du produit anti-PPP1CA anticorps

Fonction: PPP1CA Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human PPP1CA expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PPP1CA (ABIN969360)

Chen, Kesler, Paschal, Balk: "Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1." dans: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25576-84, (2009) (PubMed).

Perry, Yang, Soora, Salma, Marback, Naghibi, Ilyas, Chan, Gordon, McDermott: "Direct interaction between myocyte enhancer factor 2 (MEF2) and protein phosphatase 1alpha represses MEF2-dependent gene expression." dans: Molecular and cellular biology, Vol. 29, Issue 12, pp. 3355-66, (2009) (PubMed).

Détails sur PPP1CA

Antigène: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Autre désignation: PPP1CA

Sujet: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 38 kDa

ID gène: 5499

UniProt: P62136

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism