TGFB1 anticorps

N° du produit ABIN969435

Détail du produit anti-TGFB1 anticorps

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFB1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of TGF beta1 expressed in E. coli.

Clone: 4F9C10

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-TGFB1 (ABIN969435)

Saika: "TGFbeta pathobiology in the eye." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 86, Issue 2, pp. 106-15, (2006) (PubMed).

Boche, Cunningham, Docagne, Scott, Perry: "TGFbeta1 regulates the inflammatory response during chronic neurodegeneration." dans: Neurobiology of disease, Vol. 22, Issue 3, pp. 638-50, (2006) (PubMed).

Détails sur TGFB1

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Autre désignation: TGF beta1 (TGFB1 Produits)

Synonymes: anticorps CED, anticorps DPD1, anticorps LAP, anticorps TGFB, anticorps TGFbeta, anticorps TGF-beta, anticorps TGF-BETA-1, anticorps TGF-beta5, anticorps ced, anticorps dpd1, anticorps lap, anticorps tgf-beta, anticorps tgfb, anticorps tgfb5, anticorps tgfbeta, anticorps TGF-beta1, anticorps TGFbeta1, anticorps Tgfb, anticorps Tgfb-1, anticorps ai39657, anticorps tgfb1, anticorps wu:fb13a07, anticorps xx:ai39657, anticorps TGFB1, anticorps csd, anticorps cdb1, anticorps cdg2, anticorps csd1, anticorps csd2, anticorps csd3, anticorps ebmd, anticorps lcd1, anticorps bigh3, anticorps cdgg1, anticorps betaig-h3, anticorps TGFB4, anticorps transforming growth factor beta 1, anticorps transforming growth factor beta-1, anticorps transforming growth factor beta 1 L homeolog, anticorps transforming growth factor, beta 1, anticorps transforming growth factor, beta 1a, anticorps transforming growth factor beta induced L homeolog, anticorps TGFB1, anticorps Tgfb1, anticorps tgfb1.L, anticorps tgfb1a, anticorps tgfbi.L

Sujet:

Description: TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.

Aliases: CED, DPD1, TGFB, TGFbeta, TGFB1

ID gène: 7040

HGNC: 7040

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints