ITGB1 anticorps

N° du produit ABIN969531

Cet anticorps anti-ITGB1 est un anticorps Souris Monoclonal détectant ITGB1 dans WB, FACS, ELISA et IHC. Adapté pour Humain et Singe. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour ITGB1 anticorps (ABIN969531)

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGB1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)

Clone: 3B6

Détail du produit anti-ITGB1 anticorps

Fonction: ITGB1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ITGB1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ITGB1 (ABIN969531)

Hamajima, Ozaki, Zhang, Iwane, Kawaguchi, Eguchi, Matsuhashi, Mizuta, Matsuzaki, Fujimoto: "Modulation of the transforming growth factor-beta1-induced Smad phosphorylation by the extracellular matrix receptor beta1-integrin." dans: International journal of oncology, Vol. 35, Issue 6, pp. 1441-7, (2009) (PubMed).

Lindberg, Ström, Lock, Gustafsson, Haldosén, Helguero: "Expression of estrogen receptor beta increases integrin alpha1 and integrin beta1 levels and enhances adhesion of breast cancer cells." dans: Journal of cellular physiology, Vol. 222, Issue 1, pp. 156-67, (2009) (PubMed).

Détails sur ITGB1

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Autre désignation: ITGB1

Sujet: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Poids moléculaire: 88.4 kDa

ID gène: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome