BRD2 Produits
(Bromodomain Containing 2 (BRD2))
Catégories
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010].
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Catégories BRD2 en vedette
BRD2 Anticorps
High quality antibodies with extensive validation data.
BRD2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BRD2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
N° du produit
ABIN5542291
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN562664
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (4)
N° du produit
ABIN7265939
Quantité
100 μL
Fiche technique
Fiche technique
BRD2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN428131
Quantité
96 tests
Fiche technique
Fiche technique
BRD2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122047
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346854
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122048
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BRD2
: "miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons." dans: Development (Cambridge, England), Vol. 145, Issue 1, (2018) (PubMed).: "H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs." dans: Cell reports, Vol. 14, Issue 5, pp. 1142-55, (2016) (PubMed).
: "Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer." dans: Nature, Vol. 510, Issue 7504, pp. 278-82, (2014) (PubMed).
: "Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma." dans: Cancer cell, Vol. 24, Issue 5, pp. 603-16, (2013) (PubMed).
: "BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy." dans: American journal of human genetics, Vol. 73, Issue 2, pp. 261-70, (2003) (PubMed).
: "Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein." dans: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 8, pp. 1727-37, (2002) (PubMed).
: "RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F." dans: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 11, Issue 8, pp. 417-24, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à BRD2
Ring3 protein (CHLREDRAFT_190116), Ring3 protein (CHLREDRAFT_150233), Ring3 protein (CHLREDRAFT_182576), Ring3 protein (CHLREDRAFT_188250), bromodomain containing 2 (BRD2), bromodomain containing 2 (Brd2), bromodomain containing 2 S homeolog (brd2.S), bromodomain containing 2a (brd2a), AW228947, brd2, brd2-a, D6S113E, D17H6S113E, fe47f02, fi85h05, Frg-1, FSH, fsh, Fsrg-1, FSRG1, Fsrg1, fsrg1, mKIAA4005, NAT, Nat, nat, RING3, Ring3, ring3, RNF3, Rnf3, rnf3, wu:fe47f02, wu:fi85h05Protein level used designations for BRD2
- Ring3 protein
- O27.1.1
- bromodomain-containing 2
- bromodomain-containing protein 2
- female sterile homeotic-related gene 1
- really interesting new gene 3 protein
- collagen type XI alpha 2
- glutamate-cysteine ligase catalytic subunit
- ring finger protein 3
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