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BRISC and BRCA1 A Complex Member 1 Produits

(BRISC and BRCA1 A Complex Member 1 (BABAM1))

Catégories

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36. component (By similarity).

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Catégories BRISC and BRCA1 A Complex Member 1 en vedette

BRISC and BRCA1 A Complex Member 1 Anticorps

High quality antibodies with extensive validation data.

BRISC and BRCA1 A Complex Member 1 Kits ELISA

Reliable ELISA kits for a wide range of species.

BRISC and BRCA1 A Complex Member 1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BRISC and BRCA1 A Complex Member 1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN652514
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN949228
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Dog, Guinea Pig, Horse, Human, Monkey, Mouse
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN6749759
Quantité 100 μL
Fiche technique Fiche technique

BRISC and BRCA1 A Complex Member 1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1124172
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1124171
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1124173
Quantité 96 tests
Fiche technique Fiche technique

BRISC and BRCA1 A Complex Member 1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122038
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1347280
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3089878
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BRISC and BRCA1 A Complex Member 1

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à BRISC and BRCA1 A Complex Member 1

BRISC and BRCA1 A complex member 1 (babam1), BRISC and BRCA1 A complex member 1 (BABAM1), BRISC and BRCA1 A complex member 1 L homeolog (babam1.L), BRISC and BRCA1 A complex member 1 (Babam1), 5430437P03Rik, C7H19orf62, c19orf62, C19orf62, merit40, MERIT40, Merit40, nba1, NBA1, zgc:100909

Protein level used designations for BRISC and BRCA1 A Complex Member 1

  • BRCA1-A complex subunit MERIT40
  • BRISC and BRCA1-A complex member 1
  • mediator of RAP80 interactions and targeting subunit of 40 kDa
  • new component of the BRCA1-A complex
  • mediator of Rap80 interactions and targeting 40 kDa
  • new component of the BRCA1 A complex
  • new component of the BRCAA1 A complex
  • Uncharacterized protein C19orf62 homolog
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