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CASP14 Produits

(Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008].

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Catégories CASP14 en vedette

CASP14 Anticorps

High quality antibodies with extensive validation data.

CASP14 Kits ELISA

Reliable ELISA kits for a wide range of species.

CASP14 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CASP14 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN565119
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Dog, Gerbil, Human, Mouse, Rat
Application WB, IP, IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN537403
Quantité 50 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
N° du produit ABIN3030293
Quantité 100 μg
Fiche technique Fiche technique

CASP14 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6954413
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965457
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965455
Quantité 96 tests
Fiche technique Fiche technique

CASP14 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348095
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3090559
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3090561
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CASP14

Sinha, P K: "Enhanced Induction of Apoptosis in HaCaT Cells by Luteolin Encapsulated in PEGylated Liposomes-Role of Caspase-3/Caspase-14." dans: Applied biochemistry and biotechnology, Vol. 188, Issue 1, pp. 147-164, (2019) (PubMed).

Mcheik, Barrault, Pedretti, Garnier, Juchaux, Levard, Morel, Lecron, Bernard: "Foreskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts." dans: Journal of tissue engineering and regenerative medicine, Vol. 10, Issue 3, pp. 252-60, (2016) (PubMed).

Chamcheu, Adhami, Esnault, Sechi, Siddiqui, Satyshur, Syed, Dodwad, Chaves-Rodriquez, Longley, Wood, Mukhtar: "Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice." dans: Antioxidants & redox signaling, (2016) (PubMed).

Dang, Pang, Song, An, Ma: "Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes." dans: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 28-33, (2016) (PubMed).

George, Kumar, Suresh, Kumar: "Luteolin induces caspase-14-mediated terminal differentiation in human epidermal keratinocytes." dans: In vitro cellular & developmental biology. Animal, Vol. 51, Issue 10, pp. 1072-6, (2015) (PubMed).

Mcheik, Barrault, Pedretti, Garnier, Juchaux, Levard, Morel, Bernard, Lecron: "Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children." dans: Burns : journal of the International Society for Burn Injuries, Vol. 41, Issue 2, pp. 352-8, (2015) (PubMed).

Jung, Choi, Lee, Kim, Hwang, Choi: "Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis." dans: Journal of dermatological science, Vol. 76, Issue 3, pp. 231-9, (2014) (PubMed).

Ratovitski: "Phospho-?Np63? regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation." dans: FEBS letters, Vol. 587, Issue 21, pp. 3581-6, (2013) (PubMed).

Murakami, Okamura, Aoki, Sakagami, Yamazaki: "Association of caspase-14 and filaggrin expression with keratinization of the oral mucosa and reconstruction culture rat models." dans: Journal of periodontal research, (2013) (PubMed).

Wu, Kodani, Dickinson, Huff, Ogbureke, Qin, Arun, Dulebohn, Al-Shabrawey, Tawfik, Prater, Lewis, Wataha, Messer, Hsu: "Exogenous expression of caspase-14 induces tumor suppression in human salivary cancer cells by inhibiting tumor vascularization." dans: Anticancer research, Vol. 29, Issue 10, pp. 3811-8, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à CASP14

caspase 14, apoptosis-related cysteine peptidase (CASP14), caspase 14 (Casp14), caspase 14 (CASP14), caspase-14-like (LOC485601), caspase-14 (LOC780455), CASP14, MICE, mini-ICE

Protein level used designations for CASP14

  • caspase 14
  • CASP-14
  • caspase-14
  • apoptosis-related cysteine protease
  • caspase 14, apoptosis-related cysteine protease
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