CASP5 Produits
(Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
Catégories
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc\\/Max\\/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein\\\\; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010].
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Catégories CASP5 en vedette
CASP5 Anticorps
High quality antibodies with extensive validation data.
CASP5 Kits ELISA
Reliable ELISA kits for a wide range of species.
CASP5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CASP5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (4)
N° du produit
ABIN7432568
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (4)
N° du produit
ABIN654898
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (5)
N° du produit
ABIN3030309
Quantité
0.4 mL
Fiche technique
Fiche technique
CASP5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965469
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954421
Quantité
96 tests
Fiche technique
Fiche technique
CASP5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348109
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN3090740
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7391987
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CASP5
: "Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy. ..." dans: The Journal of allergy and clinical immunology, (2019) (PubMed).: "Differential Effects of Dexamethasone and Doxycycline on Inflammation and MMP Production in Murine Alkali-Burned Corneas Associated with Dry Eye." dans: The ocular surface, Vol. 14, Issue 2, pp. 242-54, (2016) (PubMed).
: "Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas." dans: Investigative ophthalmology & visual science, Vol. 56, Issue 8, pp. 4908-18, (2015) (PubMed).
: "Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens." dans: Cell host & microbe, Vol. 16, Issue 2, pp. 249-56, (2014) (PubMed).
: "Expression and functional roles of caspase-5 in inflammatory responses of human retinal pigment epithelial cells." dans: Investigative ophthalmology & visual science, Vol. 52, Issue 12, pp. 8646-56, (2011) (PubMed).
: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." dans: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).
: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." dans: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).
: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." dans: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).
: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." dans: Cell, Vol. 117, Issue 5, pp. 561-74, (2004) (PubMed).
: "Interleukin-18." dans: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à CASP5
caspase 5 (CASP5), caspase-5 (LOC100437308), CASP5, ICE(rel)III, ICEREL-III, ICH-3Protein level used designations for CASP5
- CASP-5
- ICE(rel)-III
- TY protease
- caspase 5, apoptosis-related cysteine protease
- caspase-5
- protease ICH-3
- protease TY
- caspase 5
- caspase 5, apoptosis-related cysteine peptidase
- caspase-5-like
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