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Human Monoclonal ARHGAP6 Primary Antibody pour ELISA, WB - ABIN559940
Potet, Petersen, Boutaud, Shuai, Stepanovic, Balser, Kupershmidt: Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator. dans Journal of molecular and cellular cardiology 2009
Human Monoclonal ARHGAP6 Primary Antibody pour ELISA, WB - ABIN513485
Almog, Lazar, Reiss, Etkovitz, Milch, Rahamim, Dobkin-Bekman, Rotem, Kalina, Ramon, Raziel, Breitbart, Brietbart, Seger, Naor: Identification of extracellular signal-regulated kinase 1/2 and p38 MAPK as regulators of human sperm motility and acrosome reaction and as predictors of poor spermatozoan quality. dans The Journal of biological chemistry 2008
ARHGAP6 was found to have low expression in tumor tissues from patients with lung cancer, accompanied by high expression of MMP9 and VEGF. In A549 and H1299 cells, upregulation of ARHGAP6 inhibited tumor growth and metastasis and reduced the levels of MMP9, VEGF and pSTAT3, while the levels STAT3 were unchanged.
Failed ARHGAP6 expression did not appreciably alter the severity of enamel defects when AMELX was absent.
the RhoGAP6 isoform 1 variant might serve as a biomarker for the development and progression of colorectal cancer
Human ARHGAP6 protein possessing GTPase stimulating activity for RhoA on the catalytic properties of PLC-delta1, was studied.
Analysis of Mid1, Hccs, Arhgap6, and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf) mutant mice
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Rho GTPase activating protein 6
, rho GTPase-activating protein 6
, rho GTPase-activating protein 6-like
, Rho-type GTPase-activating protein RhoGAPX-1
, rho-type GTPase-activating protein 6
, rho-type GTPase-activating protein RhoGAPX-1