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CTLA4 Protéines

(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].

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CTLA4 Protein (AA 36-161) (mFc-His Tag)

CTLA4 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS

Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.

Flow cytometry analysis with 1 μg/mL Human C Protein, mFc-His tag (ABIN6961090, ABIN7042209 and ABIN7042210) on Expi293 cells transfected with human B7-1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human B7-1, hFc tagged protein ABIN6961158, ABIN7042345 and ABIN7042346 can bind Human C, mFc-His tagged protein (ABIN6961090, ABIN7042209 and ABIN7042210) in a linear range of 0.

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human B7-2, hFc tagged protein ABIN6961159, ABIN7042347 and ABIN7042348 can bind Human C, mFc-His tagged protein (ABIN6961090, ABIN7042209 and ABIN7042210) in a linear range of 0.

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CTLA-4, mFc-His tagged protein (ABIN6961090, ABIN7042209 and ABIN7042210) can bind Anti-CTLA-4 Neutralizing antibody ABIN6964435 and ABIN7272571 in a linear range of 0.

cell line transfected with irrelevant protein (B) and human B7-2 (A) were surface stained with Human C, mFc-His tagged protein (ABIN6961090, ABIN7042209 and ABIN7042210) 1 μg/mL followed by Alexa 488-conjugated anti-mouse IgG secondary antibody.

6 images

N° du produit ABIN6961090

CTLA4 Protein (AA 36-161) (His-Avi Tag,Biotin)

CTLA4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Biotinylated Human CTLA4 on Tris-Bis PAGE under reduced condition.

Immobilized Biotinylated Human CTLA-4, His Tag at 0.

The purity of Biotinylated Human CTLA4 is greater than 95 % as determined by SEC-HPLC.

Immobilized Biotinylated Human CTLA4, His Tag at 0.

Immobilized Human B7-1, hFc Tag at 1 μg/mL (100 μL/Well) on the plate.

5 images

N° du produit ABIN7274437

CTLA4 Protein (AA 37-160) (His tag)

CTLA4 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Cynomolgus CTLA-4 on Tris-Bis PAGE under reduced condition.

Immobilized Cynomolgus CTLA-4, His Tag at 1 μg/mL (100 μL/well) on the plate.

The purity of Cynomolgus CTLA-4 is greater than 95 % as determined by SEC-HPLC.

Cynomolgus B7-1, His Tag immobilized on CM5 Chip can bind Cynomolgus CTLA-4, His Tag with an affinity constant of 9.

4 images

N° du produit ABIN7274434

CTLA4 Protein (AA 36-161) (Fc Tag)

CTLA4 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS

Human CTLA-4 Protein, hFc Tag on SDS-PAGE under reducing condition.

Flow cytometry analysis with 1 μg/mL Human C Protein, hFc tag (ABIN6961164, ABIN7042357 and ABIN7042358) on Expi293 cells transfected with human B7-1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

cell line transfected with irrelevant protein (B) and human B7-2 (A) were surface stained with Human C, hFc tagged protein (ABIN6961164, ABIN7042357 and ABIN7042358) 1 μg/mL followed by Alexa 488-conjugated anti-human IgG secondary antibody.

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CTLA-4, hFc tagged protein (ABIN6961164, ABIN7042357 and ABIN7042358) can bind Anti-C Neutralizing antibody ABIN6964435 and ABIN7272571 in a linear range of 0.

4 images

N° du produit ABIN6961164

CTLA4 Protein (AA 37-162) (His tag)

CTLA4 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Human CTLA-4, His Tag on SDS-PAGE under reducing (R) condition.

Immobilized Human B7-2, Fc Tag with a linear range of 1-6.

Immobilized Human B7-1, Fc Tag with a linear range of 0.

3 images

3 références

N° du produit ABIN2487344

CTLA4 Protein (AA 36-162) (His tag)

CTLA4 Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Mouse CTLA-4, His Tag on SDS-PAGE under reducing (R) condition.

Immobilized Mouse B7-2, Fc Tag (Cat# CD6-M5251) at 5 μg/mL (100 µl/well),can bind Mouse CTLA-4, His Tag (Cat# CT4-M52H5) with a linear range of 0.

Immobilized Mouse B7-1, Fc Tag (Cat# CD0-M5259) at 2 μg/mL (100 µl/well),can bind Mouse CTLA-4, His Tag (Cat# CT4-M52H5) with a linear range of 0.

3 images

1 reference

N° du produit ABIN2870729

CTLA4 Protein (AA 37-162) (Fc Tag,AVI tag,Biotin)

CTLA4 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active

Biotinylated Human CTLA-4, Fc tag on SDS-PAGE under reducing (R) condition.

Immobilized Human B7-1, Fc Tag (Cat# B71-H5259) at 5 μg/mL (100 µl/well),can bind Biotinylated Human CTLA-4, Fc tag (Cat# CT4-H82F3) with a linear range of 0.

Immobilized Human B7-2, Fc Tag (Cat# CD6-H5257) at 5 μg/mL (100 µl/well),can bind Biotinylated Human CTLA-4, Fc tag (Cat# CT4-H82F3) with a linear range of 2-30 ng/mL.

3 images

1 reference

N° du produit ABIN2870534

CTLA4 Protein (His tag)

CTLA4 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active

ELISA image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag) (ABIN7320509)

Western Blotting (WB) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag) (ABIN7320509)

2 images

N° du produit ABIN7320509

CTLA4 Protein (His tag)

CTLA4 Origine: Cobaye Hôte: Yeast (Pichia pastoris) Recombinant > 90 % as determined by reducing SDS-PAGE. Active

ELISA image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag) (ABIN7321017)

Western Blotting (WB) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag) (ABIN7321017)

2 images

N° du produit ABIN7321017

CTLA4 Protein (AA 37-161) (His-DYKDDDDK-Strep II Tag)

CTLA4 Origine: Humain Hôte: HEK-293T Cells Recombinant WB, SDS, ELISA, PI

SDS-PAGE (SDS) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-161) protein (His-DYKDDDDK-Strep II Tag) (ABIN4369863)

Western Blotting (WB) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-161) protein (His-DYKDDDDK-Strep II Tag) (ABIN4369863)

2 images

N° du produit ABIN4369863

CTLA4 Protein (AA 37-160) (His tag)

CTLA4 Origine: Cynomolgus, Macaque rhésus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Cynomolgus CTLA-4, His Tag on SDS-PAGE under reducing (R) condition.

Immobilized Cynomolgus / Rhesus macaque B7-2, Fc Tag (ABIN2180852,ABIN2180851) at 2 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque CTLA-4, His Tag (ABIN2180926,ABIN2180925) with a linear range of 4-31 ng/mL (Routinely tested).

Immobilized Cynomolgus / Rhesus macaque B7-1, Fc Tag (ABIN2870586,ABIN2870587) at 2 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque CTLA-4, His Tag (ABIN2180926,ABIN2180925) with a linear range of 0.

3 images

N° du produit ABIN2180926

CTLA4 Protein (AA 36-162) (Fc Tag)

CTLA4 Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Mouse CTLA-4, Fc Tag on SDS-PAGE under reducing (R) condition.

Immobilized Mouse B7-1, His Tag with a linear range of 0.

2 images

1 reference

N° du produit ABIN2870731

CTLA4 Protein (AA 36-162) (His tag,AVI tag,Biotin)

CTLA4 Origine: Souris Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active

Biotinylated Mouse CTLA-4, His,Avitag on under reducing (R) condition.

Immobilized Biotinylated Mouse CTLA-4, His,Avitag (ABIN6973042) at 1 μg/mL (100 μL/well) on Streptavidin precoated (0.

Immobilized Mouse B7-1, Fc Tag (ABIN2870712,ABIN2870713) at 5 μg/mL (100 μL/well) can bind Biotinylated Mouse CTLA-4, His,Avitag (ABIN6973042) with a linear range of 0.

3 images

N° du produit ABIN6973042

CTLA4 Protein (AA 37-160) (His tag,AVI tag,Biotin)

CTLA4 Origine: Cynomolgus, Macaque rhésus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Biotinylated Cynomolgus CTLA-4 on SDS-PAGE under reducing (R) condition.

Immobilized Human B7-2, Fc Tag (ABIN2180621,ABIN2180620) at 5 μg/mL (100 μL/well) can bind Biotinylated Cynomolgus / Rhesus macaque CTLA-4, Avitag,His Tag (ABIN2180929,ABIN3071725) with a linear range of 2-63 ng/mL (Routinely tested).

Immobilized Human B7-1, Fc Tag (ABIN2180846,ABIN2180845) at 2 μg/mL (100 μL/well) can bind Biotinylated Cynomolgus / Rhesus macaque CTLA-4, Avitag,His Tag (ABIN2180929,ABIN3071725) with a linear range of 2-31 ng/mL (QC tested).

3 images

N° du produit ABIN2180929

CTLA4 Protein (AA 37-162) (Strep Tag)

CTLA4 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

Human CTLA-4, Strep Tag on SDS-PAGE under reducing (R) condition.

Immobilized Recombinant Human B7-2 / CD86 Protein, With C-Fc Tag with a linear range of 1-20 ng/mL.

Immobilized Recombinant Human CD80 /B7-1 Protein, With C-Fc Tag with a linear range of 1-20 ng/mL.

3 images

N° du produit ABIN6810026

CTLA4 Protein (DYKDDDDK Tag)

CTLA4 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by SDS-PAGE

Western Blotting (WB) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) protein (DYKDDDDK Tag) (ABIN7320508)

1 image

N° du produit ABIN7320508

CTLA4 Protein (Fc Tag)

CTLA4 Origine: Cynomolgus Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.

Western Blotting (WB) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) protein (Fc Tag) (ABIN7320970)

1 image

N° du produit ABIN7320970

CTLA4 Protein (AA 36-135) (GST tag)

CTLA4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP

Image no. 1 for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-135) protein (GST tag) (ABIN1350656)

1 image

N° du produit ABIN1350656

CTLA4 Protein (His tag,ECD)

CTLA4 Origine: Rat Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE

Western Blotting (WB) image for Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) protein (His tag,ECD) (ABIN7195370)

1 image

N° du produit ABIN7195370

CTLA4 Protéine

CTLA4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant SDS

Figure annotation denotes ug of protein loaded and % gel used.

1 image

N° du produit ABIN2128753

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