CTNNA1 Produits
(Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
Catégories
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
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Catégories CTNNA1 en vedette
CTNNA1 Anticorps
High quality antibodies with extensive validation data.
CTNNA1 Kits ELISA
Reliable ELISA kits for a wide range of species.
CTNNA1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CTNNA1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (7)
N° du produit
ABIN6260492
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP
Validations
- (8)
N° du produit
ABIN6139202
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN7261582
Quantité
200 μL
Fiche technique
Fiche technique
CTNNA1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954435
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380986
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Pig
Analytical Method
Quantitative
Validations
N° du produit
ABIN778448
Quantité
96 tests
Fiche technique
Fiche technique
CTNNA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350658
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350660
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3091997
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CTNNA1
: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." dans: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).: "DLC1 interaction with ?-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity." dans: Molecular and cellular biology, Vol. 32, Issue 11, pp. 2145-59, (2012) (PubMed).
: "Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells." dans: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18252-9, (2009) (PubMed).
: "Deconstructing the cadherin-catenin-actin complex." dans: Cell, Vol. 123, Issue 5, pp. 889-901, (2005) (PubMed).
: "Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly." dans: Cell, Vol. 123, Issue 5, pp. 903-15, (2005) (PubMed).
: "Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin." dans: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12758-65, (2005) (PubMed).
: "Gastric cancer: new genetic developments." dans: Journal of surgical oncology, Vol. 90, Issue 3, pp. 114-33; discussion 133, (2005) (PubMed).
: "Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma." dans: World journal of gastroenterology, Vol. 10, Issue 22, pp. 3235-9, (2005) (PubMed).
: "Characterization of cadherin-24, a novel alternatively spliced type II cadherin." dans: The Journal of biological chemistry, Vol. 278, Issue 30, pp. 27513-9, (2003) (PubMed).
: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à CTNNA1
catenin alpha 1 (CTNNA1), catenin (cadherin associated protein), alpha 1 (Ctnna1), catenin alpha 1 (Ctnna1), alpha Catenin (alpha-Cat), alpha Catenin (Dgri\alpha-Cat), catenin alpha-1 (Tsp_10127), catenin (cadherin-associated protein), alpha 1 (ctnna1), catenin alpha 1 S homeolog (ctnna1.S), 2010010M04Rik, a-Cat, a-cat, AA517462, AI988031, alpha-CAT, alpha-cat, Alpha-Cat, alpha-catenin, alpha-ctn, alphaCAT, alphaCat, alphacat, CAP102, cap102, Catna1, catna1, CG17947, CT39986, ctnna, ctnna1, Dalpha-Cat, Dalpha-cat, DalphaC, Dalphacat, DgriGH19548, dgri_GLEANR_3829, Dmcatp, Dmel\\CG17947, GH19548Protein level used designations for CTNNA1
- alpha E-catenin
- alpha-E-catenin
- alpha-catenin
- alphaE-catenin
- cadherin-associated protein,102kDa
- catenin alpha-1
- renal carcinoma antigen NY-REN-13
- a-catenin
- 102 kDa cadherin-associated protein
- CAP102
- alpha E catenin
- alpha(E)-catenin
- cadherin associated protein
- catenin alpha 1
- catenin (cadherin associated protein), alpha 1
- catenin, alpha 1
- CG17947-PA
- D-alpha-catenin
- Dalpha-Catenin
- Dalpha-cadherin
- DalphaCatenin
- alpha catenin
- alpha-Cat-PA
- alpha-Catenin
- alphaCatenin
- catenin alpha 1 subunit
- DgriGH19548-PA
- Dgrialpha-Cat-PA
- GH19548-PA
- catenin (cadherin-associated protein), alpha 1, 102kDa
- catenin alpha-1-like
- [a]E-catenin
- catenin alpha 1 S homeolog
- LOW QUALITY PROTEIN: catenin alpha-1
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