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DBN1 Produits

(Drebrin 1 (DBN1))
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories DBN1 en vedette

DBN1 Anticorps

High quality antibodies with extensive validation data.

DBN1 Kits ELISA

Reliable ELISA kits for a wide range of species.

DBN1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DBN1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC, StM
Validations
  • (5)
N° du produit ABIN6939227
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application FACS
Validations
  • (1)
  • (3)
N° du produit ABIN1558085
Quantité 100 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6261368
Quantité 100 μL
Fiche technique Fiche technique

DBN1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955457
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5608558
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5690868
Quantité 96 tests
Fiche technique Fiche technique

DBN1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1351156
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122708
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3078985
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DBN1

Richter, Wildhagen, Helm, Ußling, Schikorski, Rizzoli: "Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins." dans: Scientific reports, Vol. 8, Issue 1, pp. 14838, (2018) (PubMed).

Bhat, Thirumangalakudi: "Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet." dans: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 4, pp. 781-9, (2013) (PubMed).

Vaskova, Kovac, Volna, Angelisova, Mejstrikova, Zuna, Brdicka, Hrusak: "High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody." dans: Leukemia research, Vol. 35, Issue 8, pp. 1111-3, (2011) (PubMed).

Chen, Prior, Dargusch, Roberts, Riek, Eichmann, Chiruta, Akaishi, Abe, Maher, Schubert: "A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease." dans: PLoS ONE, Vol. 6, Issue 12, pp. e27865, (2011) (PubMed).

Park, Yamada, Kojo, Sato, Onozuka, Yamamoto: "Drebrin (developmentally regulated brain protein) is associated with axo-somatic synapses and neuronal gap junctions in rat mesencephalic trigeminal nucleus." dans: Neuroscience letters, Vol. 461, Issue 2, pp. 95-9, (2009) (PubMed).

Maezawa, Nivison, Montine, Maeda, Montine: "Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 6, pp. 797-9, (2006) (PubMed).

Ganong, Kramer, Salmon, Reid, Lovinger, Scapagnini, Boryczka, Shackelford: "Pharmacological evidence for inhibition of ACTH secretion by a central adrenergic system in the dog." dans: Neuroscience, Vol. 1, Issue 3, pp. 167-74, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à DBN1

drebrin 1 (DBN1), drebrin 1 (Dbn1), drebrin 1 S homeolog (dbn1.S), drebrin 1 (dbn1), D0S117E, DBN1, LOC733967

Protein level used designations for DBN1

  • developmentally-regulated brain protein
  • drebrin
  • drebrin E
  • drebrin E2
  • drebrin-1
  • drebrin A
  • developmentally regulated brain protein
  • drebrin 1
  • drebrin-like
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