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anti-Human SLC19A1 Anticorps:
anti-Mouse (Murine) SLC19A1 Anticorps:
anti-Rat (Rattus) SLC19A1 Anticorps:
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Human Polyclonal SLC19A1 Primary Antibody pour IHC, WB - ABIN2781749
Payton, Liu, Ge, Matherly: Transcriptional regulation of the human reduced folate carrier A1/A2 promoter: Identification of critical roles for the USF and GATA families of transcription factors. dans Biochimica et biophysica acta 2005
Show all 3 Pubmed References
RFC, IL15 and VDR germline variants are associated with minimal residual disease in pediatric B-cell precursor ALL
We identified eight novel variants in SLC19A1 and twelve novel variants in FOLR1 (Montrer FOLR1 Anticorps), FOLR2 (Montrer FOLR2 Anticorps), and FOLR3 (Montrer FOLR3 Anticorps). Pathogenic variants include c.1265delG in SLC19A1 resulting in an early stop codon, four large insertion deletion variants in FOLR3 (Montrer FOLR3 Anticorps), and a stop_gain variant in FOLR3 (Montrer FOLR3 Anticorps)
Reduced SLC19A1 expression in human adipocytes induces DNA hypermethylation, resulting in increased expression of specific proinflammatory genes, including CCL2 (Montrer CCL2 Anticorps). This constitutes an epigenetic mechanism that might link dysfunctional adipocytes to white adipose tissue inflammation and Insulin (Montrer INS Anticorps) resistance.
data suggested that the RFC1 (Montrer RFC1 Anticorps) A80G G allele was an APOE (Montrer APOE Anticorps) 4-independent risk factor for late-onset Alzheimer's disease (AD
MTHFR (Montrer MTHFR Anticorps) 677C/T and RFC1 (Montrer RFC1 Anticorps) 80G/A polymorphisms may serve as predictors of toxicity during maintenance chemotherapy in childhood acute lymphoblastic leukemia or lymphoma.
Neonatal RFC1 (Montrer RFC1 Anticorps) polymorphism influenced total homocysteinein neonates
There was an association between RFC1 (Montrer RFC1 Anticorps) A80G variant and the risk of nonsymdromic cleft lip with or without palate.
the G80A mutation in the RFC1 (Montrer RFC1 Anticorps) gene is associated with a greater risk for sporadic breast cancer and oxidative DNA damage
We demonstrated no difference in tHcy, folates, vitamin B12 (Montrer NDUFB3 Anticorps) levels and allelic frequencies of C677T and G80A polymorphisms in MTHFR (Montrer MTHFR Anticorps) and RFC (Montrer RFC1 Anticorps) genes between obese and no obese Tunisian children.
677T and 1298C alleles of MTHFR (Montrer MTHFR Anticorps) and G80 RFC-1 (Montrer RFC1 Anticorps) show association with hyperhomocysteinemia.
The mRNAs encoding Folr2 and the intestinal folate transporter Slc46a1 were not detected in 2-cel embryos and blastocysts.
Interleukin-6 (Montrer IL6 Anticorps) regulated the efficacy of methotrexate by decreasing the expression of SLC19A1.
First evidence of RFC expression in rapidly dividing cells of developing neural tube, craniofacial region, limb buds and heart duggests that these regions may be particularly susceptible to folate deficiency.
Inactivation of RFC1 (Montrer RFC1 Anticorps) impacts the expression of several ligands and interacting proteins in the cubilin (Montrer CUBN Anticorps)-amnionless (Montrer AMN Anticorps)-megalin (Montrer LRP2 Anticorps) complex that are involved in the maternal-fetal transport of folate and other nutrients.
Intestinal folate uptake process undergoes differentiation-dependent regulation and that this regulation is mediated via changes in the level of expression of both the RFC and PCFT (Montrer SLC46A1 Anticorps).
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.
solute carrier family 19 (folate transporter), member 1
, folate transporter 1
, intestinal folate carrier 1
, placental folate transporter
, reduced folate carrier protein
, solute carrier family 19 member 1
, intestinal folate carrier protein
, reduced folate carrier 1
, solute carrier family 19 (sodium/hydrogen exchanger), member 1
, methotrexate carrier 1
, methotrexate carrier 2
, methotrexate carrier 5
, methotrexate carrier 6
, solute carrier family 19, member 1
, 58 kDa hydrophobic protein
, Folate carrier protein
, Methotrexate uptake protein
, Solute carrier family 19 member 1