anti-Souris Teratocarcinoma-Derived Growth Factor 1 anticorps pour Western Blotting

Recommended Teratocarcinoma-Derived Growth Factor 1 Antibody

Antigène
Teratocarcinoma-Derived Growth Factor 1 (TDGF1) Anticorps
  • CR
  • CRGF
  • CRIPTO
  • CR1
  • cripto
  • cb85
  • tdgf1
  • wu:fe01d04
  • zgc:109829
  • Cripto-1
  • cr1
  • cr1a
  • frl-1
  • frl1
  • xcr1
  • TDGF1
  • tdgf3
  • cripto-3
  • teratocarcinoma-derived growth factor 1
  • teratocarcinoma-derived growth factor 1, member 3 L homeolog
  • teratocarcinoma-derived growth factor 1, member 1
  • TDGF1
  • Tdgf1
  • tdgf1
  • tdgf1.3.L
  • tdgf1.1
Reactivité
Souris, Rat (Rattus), Humain
170
54
50
2
2
Hôte
Lapin
125
42
13
2
Clonalité
Polyclonal
Conjugué
Inconjugué
16
15
14
6
5
5
5
5
5
5
5
5
4
4
4
4
4
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
78
74
58
52
16
6
5
2
2
2
1
1
Options

Images

N° du produit ABIN3021342
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
13.877543 ABIN2989094 IHC WB Rabbit IgG Polyclonal 0
13 ABIN1739980 WB Rabbit N-Term Polyclonal 0
10.877543 ABIN6567009 IHC WB Rabbit IgG Polyclonal 0
10.219922 ABIN151145 ICC FACS IF WB Rabbit N-Term, AA 1-50 Polyclonal 3
7.8775434 ABIN1077401 IF ELISA WB Rabbit IgG N-Term Polyclonal 0
7.8775434 ABIN6265513 ELISA IHC WB Rabbit IgG Polyclonal 0
4.8775434 ABIN6714515 IHC WB Rabbit Polyclonal 0
4.8775434 ABIN6672403 IHC WB Rabbit IgG Polyclonal 0
1 ABIN5551813 EIA WB Rabbit IgG Internal Region Polyclonal 0
1 ABIN731432 IHC (p) WB HRP Rabbit IgG Polyclonal 0
1 ABIN677957 IHC (p) WB HRP Rabbit IgG Polyclonal 0
1 ABIN731425 IHC (p) WB Biotin Rabbit IgG Polyclonal 0
1 ABIN677950 IHC (p) WB Biotin Rabbit IgG Polyclonal 0
1 ABIN731423 IF (p) IHC (p) WB Rabbit IgG Polyclonal 0
1 ABIN677948 IF (p) IHC (p) WB Rabbit IgG Polyclonal 0
1 ABIN1983706 WB Rat IgG2 AA 26-150 RM0197-3J9 0
1 ABIN2241295 WB Rabbit AA 1-50 Polyclonal 0
1 ABIN1739981 ICC WB Biotin Rabbit IgG N-Term, AA 1-50 Polyclonal 0
1 ABIN1739985 ICC WB DyLight 550 Rabbit IgG N-Term, AA 1-50 Polyclonal 0
1 ABIN1739982 ICC WB DyLight 650 Rabbit IgG N-Term, AA 1-50 Polyclonal 0

General

Antigène Teratocarcinoma-Derived Growth Factor 1 (TDGF1) Anticorps
Reactivité Souris, Rat (Rattus), Humain
(170), (54), (50), (2), (2)
Hôte Lapin
(125), (42), (13), (2)
Clonalité
Polyclonal
Conjugué Inconjugué
(16), (15), (14), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(78), (74), (58), (52), (16), (6), (5), (2), (2), (2), (1), (1)
Fournisseur

Détail du produit

Détail du antigène Information d'application Stockage Images
Purification Affinity purification
Immunogène Recombinant protein of human TDGF1
Isotype IgG

Détail du antigène

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Antigène
Autre désignation TDGF1 (TDGF1 Antibody Extrait)
Sujet Cripto, also known as teratocarcinoma derived growth factor 1 (TDGF-1), belongs to the EGF-CFC family of proteins. Members of this family are characterized by an N-terminal signal peptide, a conserved cysteine rich domain (CFC motif), and a short hydrophobic carboxy-terminal tail that contains GPI cleavage and attachment sites. The GPI moiety anchors Cripto and family members to the extracellular plasma membrane. An O-linked fucosylation site within the EGF-like motif is required for Cripto and related family members to perform their function as co-receptors for TGF-beta-related ligands such as Nodal and Vg1/GDF1. Soluble forms of Cripto can be produced - these contain intact EGF and CFC domains, and are thought to have paracrine activities, as opposed to the autocrine activity of Cripto functioning as a coreceptor. Understanding of this paracrine activity is not complete, but it is proposed that Cripto may act as co-ligand for Nodal.Cripto is an important modulator of embryogenesis and oncogenesis. It is highly expressed in early embryos, and in embryonic stem (ES) cells where it is involved in cardiomyocytic differentiation and acts as a negative regulator of neurogenesis. Transient activation of Cripto is essential for the capacity of stem cell self-renewal and pluripotency in ES cells, and in some adult derived stem cells. Signaling through Cripto can also stimulate other activities that promote tumorigenesis such as stimulation of proliferation, cell motility, invasion, angiogenesis and epithelial-mesenchymal transition (EMT). Cripto is highly expressed in a broad range of tumors, where it acts as a potent oncogene.
Synonyms: TDGF1, CR, CRGF, CRIPTO, Cripto-1
ID gène 6997
UniProt P13385
Pathways EGFR Signaling Pathway

Information d'application

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Indications d'application Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Stockage

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Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid freeze / thaw cycles
Stock -20 °C/-80 °C

Images

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Images (Fournisseur)
Western Blotting (WB) image for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN3021342) Western blot analysis of NCCIT cell lysate using TDGF1 antibody.