Profil protéine

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with OAS2

• 2'-5'-oligoadenylate synthetase 2 (OAS2) anticorps
• 2'-5' oligoadenylate synthetase 2 (Oas2) anticorps
• 2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2) anticorps

• Oasl11 anticorps

Protein level used designations for OAS2

(2'-5')oligo(A) synthetase 2 , 2'-5'-oligoadenylate synthase 2 , 2-5A synthase 2 , p69 OAS / p71 OAS , (2-5')oligo(A) synthase 2 , 2',5'-oligoadenylate synthetase-like 11 , 2'-5' oligoadenylate synthetase-like 11 , 2,5-oligoadenylate synthetase-like 11 , 2'-5'-oligoadenylate synthetase 2, 69/71kDa , 2'-5' oligoadenylate synthetase 2 , 2',5'-oligoadenylate synthetase 2 , 2'-5'-oligoadenylate synthetase 2-like , 2'-5'-oligoadenylate synthase 2-like