Tel:: +49 (0)241 95 163 153
Fax:: +49 (0)241 95 163 155
E-Mail:: orders@anticorps-enligne.fr

Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.

BMS-754807

InhA, Func 1001350-96-4

N° du produit ABIN4877233

Aperçu rapide pour BMS-754807 (ABIN4877233)

Application

Inhibition Assay (InhA), Functional Studies (Func)

Fonction

BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.

Attributs du produit

Target: IGF-1R inhibitor, c-MET inhibitor, Aurora Kinase inhibitor, FLT3 inhibitor, JAK inhibitor
Receptor: IGF-1R, Insulin Receptor,TrkB,Met,TrkA,Aurora A,Aurora B,RON,FLT3,JAK2

Purification

All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

Pureté

97 % +

Formula

C23H24FN9O

Solubility

200 mM in DMSO and ethanol
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Nicotinamide
Inh 98-92-0 Pyridine-3-carboxylic acid amide

Anacardic Acid
Inh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid

EX-527
Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)

Resveratrol
Act 501-36-0 3,4',5-Trihydroxy-trans-stilbene

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

Indications d'application

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Solid

Stock

-20 °C

Stockage commentaire

For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

Date de péremption

24 months
Sujet

JAK/STAT Signaling,Tyrosine Kinase/Adaptors

Poids moléculaire

461.49 g/mol

Numéro CAS

1001350-96-4

Vous êtes ici: