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Fedratinib (SAR302503, TG101348)

InhA, Func 936091-26-8

N° du produit ABIN3220782

113,00 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 7 à 9 jours ouvrables

Aperçu rapide pour Fedratinib (SAR302503, TG101348) (ABIN3220782)

Application

Inhibition Assay (InhA), Functional Studies (Func)

Fonction

Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Phase 2.

Attributs du produit

Tradename: Fedratinib, TG101348
Target: JAK inhibitor, FLT3 inhibitor, RET inhibitor
Receptor: JAK2/FLT3/RET

Purification

All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

Pureté

98 %

Formula

C27H36N6O3S

Solubility

100 mM in DMSO
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Nicotinamide
Inh 98-92-0 Pyridine-3-carboxylic acid amide

Anacardic Acid
Inh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid

EX-527
Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

AS-8351
Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone

Indications d'application

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Solid

Stock

-20 °C

Stockage commentaire

For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

Date de péremption

24 months
Sujet

JAK/STAT Signaling,Tyrosine Kinase/Adaptors

Poids moléculaire

524.68 g/mol

Numéro CAS

936091-26-8

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