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5-Azacytidine

Name: 5-Azacytidine
Brand: antibodies-online
SKU: ABIN7233228
Price: 75.38 EUR
Availability: InStock

Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

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N° du produit ABIN7233228

Aperçu rapide pour 5-Azacytidine (ABIN7233228)

Application

Inhibition (Inh)

Chemical Name

4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Perméabilité

Cell-permeable

Fonction

DNA hypomethylation agent

Attributs du produit

Specific inhibitor of DNA methyltransferase. Incorporates into DNA and covalently reacts with and inhibits DNA methyltransferases. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Induces cardiac differentiation of human mesenchymal stem cells by activating ERK. Induces apoptosis in multiple myeloma cells via ATR-mediated DNA double strand breaks. Cell permeable.

Pureté

>98 %

Formula

C8H12N4O5

Solubility

Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Nicotinamide
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Anacardic Acid
Inh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid

EX-527
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Resveratrol
Act 501-36-0 3,4',5-Trihydroxy-trans-stilbene

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

AS-8351
Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone

Restrictions

For Research Use only
Format

Powder

Précaution d'utilisation

GHS – Classification
Acute toxicity, Oral (Category 4), H302
Germ cell mutagenicity (Category 2), H341
Carcinogenicity (Category 1A), H350
Reproductive toxicity (Category 1B), H360
Specific target organ toxicity - repeated exposure (Category 1), H372
Long-term (chronic) aquatic hazard (Category 1), H410

Stock

-20 °C
Sujet

Ladakamycin, U-18496, NSC-102816, AzaC,Epigenetics,Chromatin,DNA methyltransferase,Stem cells,Cell death,Infectious disease,Apoptosis inducer,DNA damage

Poids moléculaire

244.2

Numéro CAS

320-67-2