Panobinostat
Aperçu rapide pour Panobinostat (ABIN7233272)
Application
Chemical Name
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Fonction
- HDAC inhibitor
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Attributs du produit
- A potent inhibitor of class I and II HDACs. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells. A potent antimyeloma agent that overcomes drug resistance.
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Pureté
- >98 %
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Formula
- C21H23N3O2
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Solubility
- Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
Anacardic AcidInh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
SAHA (Vorinostat)Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid
Phenylbutyrate NaInh 1716-12-7 4-Phenylbutyric acid, sodium salt
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Restrictions
- For Research Use only
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Format
- Powder
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Stock
- -20 °C
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Sujet
- LBH-589,Epigenetics,Apoptosis inducer,Protein deacetylase,Cell death,Cancer,Posttranslational modification,Chromatin
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Poids moléculaire
- 349.44
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Numéro CAS
- 404950-80-7
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