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Tranylcypromine hemisulfate (±)

Name: Tranylcypromine hemisulfate (±)
Brand: antibodies-online
SKU: ABIN7233300
Price: 96.92 EUR
Availability: InStock

Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt

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N° du produit ABIN7233300

Aperçu rapide pour Tranylcypromine hemisulfate (±) (ABIN7233300)

Application

Inhibition (Inh)

Chemical Name

Trans (±)-2-phenylcyclopropanamine, hemisulfate salt

Perméabilité

Cell-permeable

Fonction

Demethylase inhibitor

Attributs du produit

Irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) IC50 < 2 μM. Tranylcypromine treatment of P19 embryonal carcinoma cells resulted in global increase of H3K4 methylation along with transcriptional derepression of two BHC110 target genes, Egr1 and Oct4. When combined with CHIR99021, induces the generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Reduces proliferation, cell cycle progression and invasiveness of endometriotic stromal cells. Upregulates CD86 expression in THP1 cells. Monoamine oxidase inhibitor. Cell permeable and active in vivo.

Pureté

>98 %

Formula

C9H11N 1/2(H2SO4)

Solubility

Soluble in Water (up to 25 mg/ml).
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Restrictions

For Research Use only
Format

Powder

Stock

-20 °C
Sujet

2-PCPA, SKF-385,Epigenetics,Protein demethylase,Monoamine oxidase,Stem cells,Neuroscience,Mood disorders,Chromatin,Posttranslational Modification

Poids moléculaire

182.23

Numéro CAS

13492-01-8