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IRF3 Protein (GST tag)

IRF3 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
N° du produit ABIN1308082
  • Antigène Voir toutes IRF3 Protéines
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 3
    • 1
    • 1
    • 1
    Wheat germ
    Purification/Conjugué
    Cette IRF3 protéine est marqué à la GST tag.
    Application
    Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
    Fonction
    IRF3 (Human) Recombinant Protein (P01)
    Séquence
    MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALSRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY VRHVLSCLGG GLALWRAGQW LWAQRLGHCH TYWAVSEELL PNSGHGPDGE VPKGKEGGVF DLGPFIVGSW APRSDYLHGR KRTLTTLCPL VLCGGVMAPG PAVDQEARDG QGCAHVPQGL GRNGPGRGCL LPGEYCGPAH FQQPPTLPHL RPVQGLPAGL GGGHGFPGPW GDLSPRSSWC ASNPPVPHHL NQ
    Attributs du produit
    Human IRF3 full-length ORF ( AAH09395, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.
    Purification
    in vitro wheat germ expression system
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -80 °C
    Stockage commentaire
    Best use within three months from the date of receipt of this protein.
  • Pourcelot, Zemirli, Silva Da Costa, Loyant, Garcin, Vitour, Munitic, Vazquez, Arnoult: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." dans: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).

    Zhao, Tian, Edeh, Brasier: "Quantitation of the dynamic profiles of the innate immune response using multiplex selected reaction monitoring-mass spectrometry." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1513-29, (2013) (PubMed).

    Wang, Li, Dorf: "NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses." dans: PLoS ONE, Vol. 7, Issue 9, pp. e43756, (2012) (PubMed).

    Siu, Kok, Ng, Poon, Yuen, Zheng, Jin: "Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex." dans: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16202-9, (2009) (PubMed).

  • Antigène
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    Autre désignation
    IRF3 (IRF3 Produits)
    Synonymes
    irf3 Protein, IRF3 Protein, C920001K05Rik Protein, IRF-3 Protein, interferon regulatory factor 3 Protein, interferon regulatory factor 7 Protein, irf3 Protein, IRF3 Protein, irf-3 Protein, Irf3 Protein, IRF7 Protein
    Sujet
    Gene: interferon regulatory factor 3
    ID gène
    3661
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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