IRF3 Protein (GST tag)
-
- Antigène Voir toutes IRF3 Protéines
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Wheat germ
- Purification/Conjugué
- Cette IRF3 protéine est marqué à la GST tag.
- Application
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- Fonction
- IRF3 (Human) Recombinant Protein (P01)
- Séquence
- MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALSRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY VRHVLSCLGG GLALWRAGQW LWAQRLGHCH TYWAVSEELL PNSGHGPDGE VPKGKEGGVF DLGPFIVGSW APRSDYLHGR KRTLTTLCPL VLCGGVMAPG PAVDQEARDG QGCAHVPQGL GRNGPGRGCL LPGEYCGPAH FQQPPTLPHL RPVQGLPAGL GGGHGFPGPW GDLSPRSSWC ASNPPVPHHL NQ
- Attributs du produit
- Human IRF3 full-length ORF ( AAH09395, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.
- Purification
- in vitro wheat germ expression system
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Conseil sur la manipulation
- Aliquot to avoid repeated freezing and thawing.
- Stock
- -80 °C
- Stockage commentaire
- Best use within three months from the date of receipt of this protein.
-
-
The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." dans: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
: "Quantitation of the dynamic profiles of the innate immune response using multiplex selected reaction monitoring-mass spectrometry." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1513-29, (2013) (PubMed).
: "NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses." dans: PLoS ONE, Vol. 7, Issue 9, pp. e43756, (2012) (PubMed).
: "Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex." dans: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16202-9, (2009) (PubMed).
: "
-
The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." dans: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
-
- Antigène
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Autre désignation
- IRF3 (IRF3 Produits)
- Synonymes
- irf3 Protein, IRF3 Protein, C920001K05Rik Protein, IRF-3 Protein, interferon regulatory factor 3 Protein, interferon regulatory factor 7 Protein, irf3 Protein, IRF3 Protein, irf-3 Protein, Irf3 Protein, IRF7 Protein
- Sujet
- Gene: interferon regulatory factor 3
- ID gène
- 3661
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
-