FASL Kit ELISA

N° du produit ABIN2042460

Ce kit ELISA Humain FASL est un kit ELISA Colorimetric conçu pour quantifier Humain FASL.

Aperçu rapide pour FASL Kit ELISA (ABIN2042460)

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Competition ELISA

Gamme de detection: 15.6-1000 pg/mL

Application: ELISA

Détail du produit FASL Kit ELISA

Seuil minimal de détection: 15.6 pg/mL

Marque: BioAssay™

Réactivité croisée (Details): No detectable crossreactivity with other relevant proteins

Sensibilité: < 2 pg/mL

Ingrédients: A: Microtiter Strip, 1x96 wells
B: FASL Standard, 2x10 ng
C: Anti-human FASL (Biotin), 130 µL
: Avidin-Biotin-Peroxidase Complex (ABC), 1x130 µL (1:100 dilution)
: Sample diluent buffer, 1x30 mL
: Antibody diluent buffer, 1x10 mL
: ABC diluent buffer, 1x10 mL
: TMB color developing agent, 1x10 mL
: TMB stop solution, 2N H2SO4, 1x10 mL

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Autre désignation: FASL

Sujet: Fas ligand (FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the "target" cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7.

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity