IL-1 beta Kit ELISA
Aperçu rapide pour IL-1 beta Kit ELISA (ABIN2042515)
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Voir toutes IL-1 beta (IL1B) Kits ELISAReactivité
Méthode de détection
Type de méthode
Gamme de detection
Application
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Seuil minimal de détection
- 31.2 pg/mL
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Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensibilité
- < 1 pg/mL
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Ingrédients
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96-well plate pre-coated with anti-IL-1 beta, Rat
Lyophilized recombinant IL-1 beta, Rat standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plaque
- Pre-coated
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Protocole
- Sandwich ELISA quantitative detection kit for Rat IL-1 beta in cell culture supernates, serum and plasma (heparin, EDTA).The Interleukin 1 family is a group of 11 beta trefoil cytokines.1 Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response .2 Interleukin-1beta (IL-1beta) is a potent stimulator of bone resorption, and has been implicated in the pathogenesis of high bone turnover and osteoporosis.3 IL-1beta belongs to proinflammatory cytokines, promote cancer cell adhesion and liver metastases by up-regulating the expression of vascular cell adhesion molecule-1 (VCAM-1) on hepatic sinusoidal endothelium (HSE).4
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Restrictions
- For Research Use only
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Stock
- 4 °C/-20 °C
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Autre désignation
- Interleukin-1 beta (IL-1 Beta)
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ID gène
- 24494
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UniProt
- Q5BKB0
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Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Antigène Voir toutes IL-1 beta (IL1B) Kits ELISA
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