PEDF Kit ELISA
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- Antigène Voir toutes PEDF (SERPINF1) Kits ELISA
- PEDF (SERPINF1) (serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 0.78 ng/mL - 50 ng/mL
- Seuil minimal de détection
- 0.78 ng/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: Alpha 2 antiplasmin, Cell proliferation-inducing gene 35 protein, EPC1, OI12, OI6, PEDF, PEDF_HUMAN, PIG35, Pigment epithelium derived factor, Pigment epithelium-derived factor, Proliferation inducing protein 35, serine (or cysteine) proteinase inhibitor clade F (alpha-2 antiplasmin, pigment epithelium derived factor) member 1, SERPIN F1, Serpin peptidase inhibitor clade F member , |serpin peptidase inhibitor clade F (alpha-2 antiplasmin pigment epithelium derived factor) member 1, SERPINF1
Background: Pigment epithelium-derived factor (PEDF) is also known as serpin F1 (SERPINF1). In humans, it is encoded by the SERPINF1 gene. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. It suppresses retinal neovascularization and endothelial cell proliferation. And Antiangiogenic function is also conferred by PEDF through inhibition of both VEGFR-1 and VEGFR-2. In addition, the antitumorigenic effects of PEDF are not only due to inhibition of supporting vasculature, but also due to effects on the cancer cells themselves. PEDF is shown to inhibit cancer cell proliferation and increase apoptosis via the FAS/FASL pathway. Expression of PEDF in the human retina is found at 7.4 weeks of gestation, suggesting it may play a role in retinal neuron differentiation.
Gene Name: SERPINF1
Production: Natural and recombinant human PEDF. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: M1-P418
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- Discover our top product SERPINF1 Kit ELISA
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 50 ng/mL, 25 ng/mL, 12.5 ng/mL, 6.25 ng/mL, 3.12 ng/mL, 1.56 ng/mL, 0.78 ng/mL human PEDF standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. We recommend that each human PEDF standard solution and each sample is measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 0.78 ng/mL-50 ng/mL
Other Performance Data: DOE: 2-8° C - 12/25/18 -20° C - 6/25/19
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes PEDF (SERPINF1) Kits ELISA
- PEDF (SERPINF1) (serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
- Autre désignation
- PEDF - SerpinF1 (SERPINF1 Produits)
- Synonymes
- EPC-1 Kit ELISA, OI12 Kit ELISA, OI6 Kit ELISA, PEDF Kit ELISA, MGC82984 Kit ELISA, SERPINF1 Kit ELISA, AI195227 Kit ELISA, Pedf Kit ELISA, Pedfl Kit ELISA, Sdf3 Kit ELISA, Dmrs91 Kit ELISA, zgc:92072 Kit ELISA, serpin family F member 1 Kit ELISA, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 Kit ELISA, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog Kit ELISA, serine (or cysteine) peptidase inhibitor, clade F, member 1 Kit ELISA, SERPINF1 Kit ELISA, serpinf1 Kit ELISA, serpinf1.L Kit ELISA, Serpinf1 Kit ELISA
- ID gène
- 5176
- NCBI Accession
- NP_002606
- UniProt
- P36955
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