Helicobacter Pylori IgA (Hp-IgA) Kit ELISA

N° du produit ABIN997007

Détail du produit

Antigène: Helicobacter Pylori IgA (Hp-IgA)

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Competition ELISA

Application: ELISA

Fonction: Helicobacter pylori IgA is intended for use in evaluating the serologic status to H. pylori infection in patients with gastrointestinal symptoms.

Type d'échantillon: Serum

Analytical Method: Qualitative

Specificité: 97.10%

Sensibilité: 88.90%

Information d'application

Volume d'échantillon: 5 μL

Durée du test: 1 - 2 h

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Date de péremption: 12-18 months

Détail du antigène

Antigène: Helicobacter Pylori IgA (Hp-IgA)

Classe de substances: Antibody

Sujet: Helicobacter pylori is a spiral bacterium cultured from human gastric mucosa by Marshall in 1982. Studies have indicated that the presence of H. pylori is associated with a variety of gastrointestinal diseases including gastritis, duodenal and gastric ulcer, non-ulcer dyspepsia, gastric adenocarcinoma and lymphoma. The organism is present in 95-98% of patients with duodenal ulcer and 60-90% of patients with gastric ulcers. The studies have also demonstrated that removal of the organism by antimicrobial therapy is correlated with the resolution of symptoms and cure of diseases. Patients who present with clinical symptoms relating to the gastrointestinal tract can be diagnosed for H. pylori infection by two methods: 1) invasive techniques include biopsy followed by culture or histologic examination of biopsy specimen or direct detection of urease activity. 2) non-invasive techniques include urea breath tests, serological methods and stool antigen test. All of the testing performed on biopsy samples are subject to errors related to sampling and interference of contaminated bacteria. H. pylori IgA, testing the presence of H. pylori specific IgA antibody is the technique of choice for serologic tests because of its accuracy and simplicity.