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Leptin Receptor Produits

(Leptin Receptor (LEPR))
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010].

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Catégories Leptin Receptor en vedette

Leptin Receptor Anticorps

High quality antibodies with extensive validation data.

Leptin Receptor Kits ELISA

Reliable ELISA kits for a wide range of species.

Leptin Receptor Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Leptin Receptor recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (7)
N° du produit ABIN7430873
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7430876
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7430879
Quantité 100 μL
Fiche technique Fiche technique

Leptin Receptor recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6963259
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957442
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6963054
Quantité 96 tests
Fiche technique Fiche technique

Leptin Receptor recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Human Cells
Validations
  • (1)
N° du produit ABIN7319902
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7275141
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320922
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Leptin Receptor

Lewandowski, Biesiada, Grzesiak, Sakowicz: "C-Peptide and leptin system in dichorionic, small and appropriate for gestational age twins-possible link to metabolic programming?" dans: Nutrition & diabetes, Vol. 10, Issue 1, pp. 29, (2020) (PubMed).

Kesić, Baković, Horvatiček, Proust, Štefulj, Čičin-Šain: "Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis." dans: Frontiers in neuroscience, Vol. 14, pp. 219, (2020) (PubMed).

Balzano, De Grandis, Vu Manh, Chasson, Bardin, Farina, Sergé, Bidaut, Charbord, Hérault, Bailly, Cartier-Michaud, Boned, Dalod, Duprez, Genever, Coles, Bajenoff, Xerri, Aurrand-Lions, Schiff, Mancini: "Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche." dans: Cell reports, Vol. 26, Issue 12, pp. 3257-3271.e8, (2019) (PubMed).

Frisch, Hoffman, Latchney, LaMere, Myers, Ashton, Li, Saunders, Palis, Perkins, McCabe, Smith, McGrath, Rivera-Escalera, McDavid, Liesveld, Korshunov, Elliott, MacNamara, Becker, Calvi: "Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B." dans: JCI insight, Vol. 5, (2019) (PubMed).

Song, Li, Yang, Ning, Zhen, Wu, Zheng, Zhang, Lin, Xie, Peng: "Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow." dans: Cell death & disease, Vol. 10, Issue 5, pp. 336, (2019) (PubMed).

Zhao, Tao, Venkatraman, Li, Smith, Unruh, Chen, Ward, Qian, Perry, Marshall, Wang, He, Li: "N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells." dans: Cell reports, Vol. 26, Issue 3, pp. 652-669.e6, (2019) (PubMed).

Piattini, Le Foll, Kisielow, Rosenwald, Nielsen, Lutz, Schneider, Kopf: "A spontaneous leptin receptor point mutation causes obesity and differentially affects leptin signaling in hypothalamic nuclei resulting in metabolic dysfunctions distinct from db/db mice." dans: Molecular metabolism, Vol. 25, pp. 131-141, (2019) (PubMed).

Yamada, Odamaki, Araki, Watanabe, Matsuo, Uchida, Kato, Ozaki-Masuzawa, Takenaka: "Dietary protein restriction increases hepatic leptin receptor mRNA and plasma soluble leptin receptor in male rodents." dans: PLoS ONE, Vol. 14, Issue 7, pp. e0219603, (2019) (PubMed).

Bähr, Jahn, Zipprich, Pahlow, Spielmann, Kielstein: "Impaired natural killer cell subset phenotypes in human obesity." dans: Immunologic research, Vol. 66, Issue 2, pp. 234-244, (2019) (PubMed).

Gao, Deng, Chai, Chen, Hu, Wang, Zhu, Cao, Ni, Wan, Yang, Luo, Cao: "Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration." dans: The Journal of clinical investigation, Vol. 130, pp. 2578-2594, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à Leptin Receptor

leptin receptor (LEPR), leptin receptor (lepr), leptin receptor (Lepr), leptin receptor S homeolog (lepr.S), CD295, cd295, db, diabetes, Fa, LEP-R, lepr, Leprb, LEPRD, LEPROT, Modb1, OB-R, Ob-R, ob-rb, OB-RGRP, Ob-RM, obese-like, obl, OBR, obr, Obr, ObRb

Protein level used designations for Leptin Receptor

  • OB receptor
  • huB219
  • LEP-R
  • Leptin receptor (fatty)
  • OB-R
  • B219
  • leptin receptor gene-related protein
  • cytokine receptor
  • leptin receptor long insert isoform
  • leptin receptor
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