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LIMS1 Produits

(LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

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Catégories LIMS1 en vedette

LIMS1 Anticorps

High quality antibodies with extensive validation data.

LIMS1 Kits ELISA

Reliable ELISA kits for a wide range of species.

LIMS1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LIMS1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (2)
  • (5)
N° du produit ABIN969354
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7158341
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7237326
Quantité 200 μL
Fiche technique Fiche technique

LIMS1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957478
Quantité 96 tests
Fiche technique Fiche technique

LIMS1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309444
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309446
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3082994
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LIMS1

Yang, Wang, Hawkins, Chen, Vaynberg, Mao, Tu, Zuo, Wang, Wang, Wu, Tjandra, Qin: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." dans: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).

Chiswell, Zhang, Murphy, Boggon, Calderwood: "The structural basis of integrin-linked kinase-PINCH interactions." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, (2008) (PubMed).

Campana, Myers, Rearden: "Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury." dans: Glia, Vol. 41, Issue 3, pp. 213-23, (2003) (PubMed).

Tu, Li, Goicoechea, Wu: "The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells." dans: Molecular and cellular biology, Vol. 19, Issue 3, pp. 2425-34, (1999) (PubMed).

Tu, Li, Wu: "Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways." dans: Molecular biology of the cell, Vol. 9, Issue 12, pp. 3367-82, (1999) (PubMed).

Synonymes et noms alternatifs relatifs à LIMS1

LIM zinc finger domain containing 1 (LIMS1), LIM zinc finger domain containing 1 (Lims1), LIM and senescent cell antigen-like domains 1 (Lims1), 2310016J22Rik, 4921524A02Rik, AI507642, AU021743, AW551584, C430041B13Rik, Lims1l, LIMS3, LIMS3L, PINCH, PINCH-1, PINCH1, Pinch1, RGD1560732

Protein level used designations for LIMS1

  • LIM and senescent cell antigen-like-containing domain protein 1
  • particularly interesting new Cys-His protein 1
  • renal carcinoma antigen NY-REN-48
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