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LILRB2 Produits

(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Catégories

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories LILRB2 en vedette

LILRB2 Anticorps

High quality antibodies with extensive validation data.

LILRB2 Kits ELISA

Reliable ELISA kits for a wide range of species.

LILRB2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LILRB2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7444112
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
N° du produit ABIN5684070
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN564466
Quantité 100 μg
Fiche technique Fiche technique

LILRB2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968283
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883446
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6386002
Quantité 96 tests
Fiche technique Fiche technique

LILRB2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7275165
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275187
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275169
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LILRB2

Tomić, Ilić, Kokol, Gruden-Movsesijan, Mihajlović, Bekić, Sofronić-Milosavljević, Čolić, Vučević: "Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells." dans: International journal of nanomedicine, Vol. 13, pp. 6941-6960, (2018) (PubMed).

Lu, Li, Zhang, Xing, Sun, Yao, Chen: "Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4." dans: Nature communications, Vol. 9, Issue 1, pp. 742, (2018) (PubMed).

Zhang, Zhao, Qiu, Zhang, Li, Yang, Wei, Han, Nie, Sun: "Co-expression of ILT4/HLA-G in human non-small cell lung cancer correlates with poor prognosis and ILT4-HLA-G interaction activates ERK signaling." dans: Tumour biology, Vol. 37, Issue 8, pp. 11187-98, (2017) (PubMed).

Zhang, Yu, Li, Liu, Li, Lin, Gao, Wang, Gao, Sun: "ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer." dans: FEBS letters, Vol. 589, Issue 17, pp. 2248-56, (2015) (PubMed).

Svajger, Obermajer, Jeras: "IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses." dans: Journal of leukocyte biology, Vol. 95, Issue 1, pp. 33-46, (2014) (PubMed).

Giles, Shaw, Piper, Wong-Baeza, McHugh, Ridley, Li, Lenart, Antoniou, DiGleria, Kuroki, Maenaka, Bowness, Kollnberger: "HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 12, pp. 6184-93, (2012) (PubMed).

Yaguchi, Goto, Kido, Mochimaru, Sakurai, Tsukamoto, Kudo-Saito, Fujita, Sumimoto, Kawakami: "Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 5, pp. 2110-7, (2012) (PubMed).

Banerjee, Lin, Skinner, Schiffhauer, Peacock, Hicks, Redmond, Morrow, Huston, Shayne, Langstein, Miller-Graziano, Strickland, ODonoghue, De: "Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression." dans: Cancer research, Vol. 71, Issue 2, pp. 318-27, (2011) (PubMed).

Puddu, Latorre, Carollo, Catizone, Ricci, Valenti, Gessani: "Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells." dans: PLoS ONE, Vol. 6, Issue 7, pp. e22504, (2011) (PubMed).

Zimmer, Luce, Gaignier, Nony, Naveau, Biola-Vidamment, Pallardy, Van Overtvelt, Mascarell, Moingeon: "Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 3966-76, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à LILRB2

leukocyte immunoglobulin-like receptor subfamily A member 3 (LOC100433990), leukocyte immunoglobulin like receptor B2 (LILRB2), CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10

Protein level used designations for LILRB2

  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
  • leukocyte immunoglobulin-like receptor subfamily B member 2-like
  • CD85 antigen-like family member D
  • Ig-like transcript 4
  • leukocyte immunoglobulin-like receptor subfamily B member 2
  • monocyte/macrophage immunoglobulin-like receptor 10
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