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LRP6 Produits

(Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

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Catégories LRP6 en vedette

LRP6 Anticorps

High quality antibodies with extensive validation data.

LRP6 Kits ELISA

Reliable ELISA kits for a wide range of species.

LRP6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LRP6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC, Neut
Validations
  • (4)
N° du produit ABIN7193277
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
N° du produit ABIN390100
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Cow, Human, Mouse, Rat
Application WB, ELISA, IP, DB
Validations
  • (4)
  • (2)
N° du produit ABIN540939
Quantité 100 μg
Fiche technique Fiche technique

LRP6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957542
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6973692
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968357
Quantité 96 tests
Fiche technique Fiche technique

LRP6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275210
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN6938849
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093578
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LRP6

Priestley, Cheung, Murphy, Ehebauer, Davis, Di Daniel: "A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6." dans: Journal of pharmacological and toxicological methods, Vol. 95, pp. 47-55, (2019) (PubMed).

Du, Wang, Ye, He, Li, Du, Liu, Zhu: "Exercise training ameliorates bleomycin-induced epithelial mesenchymal transition and lung fibrosis through restoration of H2 S synthesis." dans: Acta physiologica (Oxford, England), pp. e13177, (2018) (PubMed).

Duvetorp, Olsen, Nyström, Skarstedt, Dienus, Mrowietz, Söderman, Seifert: "Expression of low-density lipoprotein-related receptors 5 and 6 (LRP5/6) in psoriasis skin." dans: Experimental dermatology, Vol. 26, Issue 11, pp. 1033-1038, (2018) (PubMed).

Xiao, Fei, Hurley: "FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation." dans: Bone reports, Vol. 9, pp. 136-144, (2018) (PubMed).

Zhu, Wang, Zhao, Zhang, Wu, Wang, Hu: "Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma." dans: Oncotarget, Vol. 8, Issue 14, pp. 22825-22834, (2017) (PubMed).

Boone, Arend, Johnston, Cooper, Gilchrist, Oelschlager, Grizzle, McGwin, Gangrade, Straughn, Buchsbaum: "Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 249-59, (2016) (PubMed).

Madan, Walker, Young, Quick, Orgel, Ryan, Gupta, Henrich, Ferrer, Marine, Roberts, Arthur, Berndt, Oliveira, Moon, Virshup, Chou, Major: "USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. E2945-54, (2016) (PubMed).

Goetzl, Boxer, Schwartz, Abner, Petersen, Miller, Carlson, Mustapic, Kapogiannis: "Low neural exosomal levels of cellular survival factors in Alzheimer's disease." dans: Annals of clinical and translational neurology, Vol. 2, Issue 7, pp. 769-73, (2015) (PubMed).

Lemieux, Cagnol, Beaudry, Carrier, Rivard: "Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer." dans: Oncogene, Vol. 34, Issue 38, pp. 4914-27, (2015) (PubMed).

Chen, Xu, Ye, Li, Gong, Zhang, Wu, Jia, Liu, Chen, Yang, Tang, Zhu, Ge, Zou: "Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 852-62, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à LRP6

LDL receptor related protein 6 (LRP6), LDL receptor related protein 6 L homeolog (lrp6.L), LDL receptor related protein 6 S homeolog (lrp6.S), low density lipoprotein receptor-related protein 6 (lrp6), LDL receptor related protein 6 (lrp6), low density lipoprotein receptor-related protein 6 (Lrp6), LDL receptor related protein 6 (Lrp6), low-density lipoprotein receptor-related protein 6 (LOC590395), adcad2, ADCAD2, C030016K15Rik, Cd, Gw, lrp6, LRP6, lrp6-A, Xlrp6

Protein level used designations for LRP6

  • low density lipoprotein receptor-related protein 6
  • lipoprotein receptor-related protein 6
  • low-density lipoprotein receptor-related protein 6
  • low-density lipoprotein receptor-related protein 6-like
  • LRP-6
  • crooked
  • low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6
  • low density lipoprotein-related protein 6
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