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LRP8 Produits

(Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011].

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Catégories LRP8 en vedette

LRP8 Anticorps

High quality antibodies with extensive validation data.

LRP8 Kits ELISA

Reliable ELISA kits for a wide range of species.

LRP8 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LRP8 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Chicken, Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
  • (4)
N° du produit ABIN719426
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (4)
N° du produit ABIN7193275
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (3)
N° du produit ABIN7439357
Quantité 100 μL
Fiche technique Fiche technique

LRP8 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968358
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957543
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5593445
Quantité 96 tests
Fiche technique Fiche technique

LRP8 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309740
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093629
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3136907
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LRP8

Arimitsu, Takai, Fujiwara, Shimizu, Ueda, Wakisaka, Hirotsu, Murayama, Suzuki, Suzuki et al.: "Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural ..." dans: Experimental neurology, Vol. 320, pp. 112970, (2019) (PubMed).

Wang, Moerman-Herzog, Slaton, Barger: "Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2." dans: Neurobiology of aging, Vol. 49, pp. 145-153, (2016) (PubMed).

Liu, Wu, Baysarowich, Kavana, Addona, Bierilo, Mudgett, Pavlovic, Sitlani, Renger, Hubbard, Fisher, Zerbinatti: "PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain." dans: Journal of lipid research, Vol. 51, Issue 9, pp. 2611-8, (2010) (PubMed).

Li, Kypreos, Zanni, Zannis: "Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain." dans: Biochemistry, Vol. 42, Issue 35, pp. 10406-17, (2003) (PubMed).

Sun, Soutar: "The transmembrane domain and PXXP motifs of ApoE receptor 2 exclude it from carrying out clathrin-mediated endocytosis." dans: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 19926-32, (2003) (PubMed).

Korschineck, Ziegler, Breuss, Lang, Lorenz, Kaun, Ambros, Binder: "Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue." dans: The Journal of biological chemistry, Vol. 276, Issue 16, pp. 13192-7, (2001) (PubMed).

Pillay, Zou, Cheng, Puschnik, Meyer, Ganaie, Deng, Wosen, Davulcu, Yan, Engelhardt, Brown, Chapman, Qiu, Carette: "AAV serotypes have distinctive interactions with domains of the cellular receptor AAVR." dans: Journal of virology (PubMed).

Synonymes et noms alternatifs relatifs à LRP8

LDL receptor related protein 8 (LRP8), low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (Lrp8), LDL receptor related protein 8 (Lrp8), 4932703M08Rik, AA921429, AI848122, APOER2, ApoER2, HSZ75190, Lr8b, LR8B, LRP-8, LRP8, MCI1

Protein level used designations for LRP8

  • low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
  • low density lipoprotein receptor-related protein 8
  • low-density lipoprotein receptor-related protein 8-like
  • ApoE receptor 2
  • low-density lipoprotein receptor-related protein 8
  • apolipoprotein E receptor 2
  • low density lipoprotein receptor relative, 8 ligand binding repeats, brain
  • LRP-8
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