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LRP5 Produits

(Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. [provided by RefSeq, Nov 2009].

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Catégories LRP5 en vedette

LRP5 Anticorps

High quality antibodies with extensive validation data.

LRP5 Kits ELISA

Reliable ELISA kits for a wide range of species.

LRP5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LRP5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (4)
N° du produit ABIN1513164
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (3)
N° du produit ABIN969535
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
  • (3)
N° du produit ABIN185410
Quantité 100 μg
Fiche technique Fiche technique

LRP5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968355
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968354
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957541
Quantité 96 tests
Fiche technique Fiche technique

LRP5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275208
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
N° du produit ABIN6809855
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275209
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LRP5

Pokharel, Mohanty, Mariasoosai, Miura, Maddison, Natesan, Bose: "Human beta defensin-3 mediated activation of β-catenin during human respiratory syncytial virus infection: interaction of HBD3 with LDL receptor-related protein 5." dans: Frontiers in microbiology, Vol. 14, pp. 1186510, (2023) (PubMed).

Duvetorp, Olsen, Nyström, Skarstedt, Dienus, Mrowietz, Söderman, Seifert: "Expression of low-density lipoprotein-related receptors 5 and 6 (LRP5/6) in psoriasis skin." dans: Experimental dermatology, Vol. 26, Issue 11, pp. 1033-1038, (2018) (PubMed).

Huang, Fantini, Merrill, Bagchi, Guzman, Raychaudhuri: "DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer." dans: Cancer research, Vol. 77, Issue 23, pp. 6562-6575, (2018) (PubMed).

Dong, Li, Li, Ren, Fan, Weng: "MicroRNA-23a-3p inhibitor decreases osteonecrosis incidence in a rat model." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 9331-9336, (2018) (PubMed).

Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." dans: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

Wehmeyer, Frank, Beckmann, Böttcher, Cromme, König, Fennen, Held, Paruzel, Hartmann, Stratis, Korb-Pap, Kamradt, Kramer, van den Berg, Kneissel, Pap, Dankbar: "Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction." dans: Science translational medicine, Vol. 8, Issue 330, pp. 330ra35, (2016) (PubMed).

Moon, Lee, Kim, Cho, Lee, Kim, Park, Cho, Lee, Oh: "Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0146710, (2016) (PubMed).

Wang, Chi, Yuan, Zhou, Yin, Zhang, Peng: "Astragaloside IV inhibits the up-regulation of Wnt/?-catenin signaling in rats with unilateral ureteral obstruction." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 5, pp. 1316-28, (2014) (PubMed).

Fei, Zhang, Huang, Xu, Zhu, Tai, Gong, Ma, Yao, Li, Zhao, Yang: "Identification of two novel LRP5 mutations in families with familial exudative vitreoretinopathy." dans: Molecular vision, Vol. 20, pp. 395-409, (2014) (PubMed).

Wiese, Gerlach, Popp, Matuszak, Mahapatro, Castiglione, Chakravortty, Willam, Hensel, Bogdan, Jantsch: "Hypoxia-mediated impairment of the mitochondrial respiratory chain inhibits the bactericidal activity of macrophages." dans: Infection and immunity, Vol. 80, Issue 4, pp. 1455-66, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à LRP5

low-density lipoprotein receptor-related protein 5 (LOC100147353), LDL receptor related protein 5 (LRP5), LDL receptor related protein 5 L homeolog (lrp5.L), low density lipoprotein receptor-related protein 5 (lrp5), LDL receptor related protein 5 (lrp5), low density lipoprotein receptor-related protein 5 (Lrp5), LDL receptor related protein 5 (Lrp5), LDL receptor related protein 5 like (LRP5L), bmnd1, BMND1, evr1, EVR1, evr4, EVR4, hbm, HBM, lr3, LR3, LRP5, lrp5-A, LRP6, lrp7, LRP7, mKIAA4142, oppg, OPPG, ops, OPS, opta1, OPTA1, vbch2, VBCH2, Xlrp5

Protein level used designations for LRP5

  • Lipoprotein Receptor Related Protein 5
  • low density lipoprotein receptor-related protein 5
  • low-density lipoprotein receptor-related protein 5
  • low-density lipoprotein receptor-related protein 5-like
  • LRP-5
  • low density lipoprotein receptor-related protein 7
  • LRP-7
  • low-density lipoprotein receptor-related protein 7
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