MAP2K7 Produits
(Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
Catégories
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008].
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Catégories MAP2K7 en vedette
MAP2K7 Anticorps
High quality antibodies with extensive validation data.
MAP2K7 Kits ELISA
Reliable ELISA kits for a wide range of species.
MAP2K7 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MAP2K7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (6)
N° du produit
ABIN969271
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (7)
N° du produit
ABIN3023157
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), PLA
Validations
- (5)
N° du produit
ABIN562438
Quantité
100 μg
Fiche technique
Fiche technique
MAP2K7 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968653
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968652
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380777
Quantité
2 x 96 tests
Fiche technique
Fiche technique
MAP2K7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN5569656
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5569657
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN5570681
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MAP2K7
: "Reactive oxygen species generated from skeletal muscles are required for gecko tail regeneration." dans: Scientific reports, Vol. 6, pp. 20752, (2017) (PubMed).: "Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium." dans: The Biochemical journal, Vol. 465, Issue 3, pp. 503-15, (2015) (PubMed).
: "Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation." dans: The Biochemical journal, Vol. 427, Issue 2, pp. 237-45, (2010) (PubMed).
: "Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3252-8, (2008) (PubMed).
: "Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK." dans: Arthritis and rheumatism, Vol. 48, Issue 9, pp. 2450-60, (2003) (PubMed).
: "Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1." dans: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15229-32, (2002) (PubMed).
: "Mixed lineage kinase ZAK utilizing MKK7 and not MKK4 to activate the c-Jun N-terminal kinase and playing a role in the cell arrest." dans: Biochemical and biophysical research communications, Vol. 297, Issue 1, pp. 105-10, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à MAP2K7
mitogen-activated protein kinase kinase 7 (MAP2K7), mitogen activated protein kinase kinase 7 (Map2k7), mitogen-activated protein kinase kinase 7 (Map2k7), mitogen-activated protein kinase kinase 7 (map2k7), mitogen-activated protein kinase kinase 7 L homeolog (map2k7.L), 2, 5930412N11Rik, JNKK, Jnkk2, JNKK 2, MAP2K7, map2k7-A, Mapkk7, MAPKK7, MAPKK 7, Mek7, MEK 7, Mkk7, MKK7, PRKMK7, Prkmk7, SAPKK-4, SAPKK4, sek2, si:ch211-254d18.2Protein level used designations for MAP2K7
- mitogen-activated protein kinase kinase 7
- JNK kinase 2
- JNK-activating kinase 2
- JNKK 2
- MAP kinase kinase 7
- MAPK/ERK kinase 7
- MAPKK 7
- MEK 7
- c-Jun N-terminal kinase kinase 2
- dual specificity mitogen-activated protein kinase kinase 7
- SAPK kinase 4
- stress-activated protein kinase kinase 4
- mitogen activated protein kinase kinase 7
- protein kinase, mitogen activated, kinase 7
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