MAP3K7 Produits
(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
Catégories
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories MAP3K7 en vedette
MAP3K7 Anticorps
High quality antibodies with extensive validation data.
MAP3K7 Kits ELISA
Reliable ELISA kits for a wide range of species.
MAP3K7 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MAP3K7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (10)
N° du produit
ABIN6256492
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN6143503
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP
Validations
- (5)
N° du produit
ABIN948522
Quantité
100 μL
Fiche technique
Fiche technique
MAP3K7 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957869
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380474
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380773
Quantité
2 x 96 tests
Fiche technique
Fiche technique
MAP3K7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (3)
- (1)
N° du produit
ABIN1310225
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570455
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310227
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MAP3K7
: "Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer." dans: Oncotarget, Vol. 6, Issue 2, pp. 995-1007, (2015) (PubMed).: "Fibroblast growth factor receptor 3 interacts with and activates TGF?-activated kinase 1 tyrosine phosphorylation and NF?B signaling in multiple myeloma and bladder cancer." dans: PLoS ONE, Vol. 9, Issue 1, pp. e86470, (2014) (PubMed).
: "Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex." dans: Journal of virology, Vol. 88, Issue 17, pp. 9830-41, (2014) (PubMed).
: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." dans: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).
: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." dans: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).
: "PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion." dans: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16441-51, (2004) (PubMed).
: "Wnt activates the Tak1/Nemo-like kinase pathway." dans: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17232-40, (2004) (PubMed).
: "Toll-like receptor signalling." dans: Nature reviews. Immunology, Vol. 4, Issue 7, pp. 499-511, (2004) (PubMed).
: "A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta." dans: Biochemical and biophysical research communications, Vol. 307, Issue 2, pp. 332-7, (2003) (PubMed).
: "Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway." dans: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36916-23, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à MAP3K7
mitogen-activated protein kinase kinase kinase 7 (map3k7), mitogen activated protein kinase kinase kinase 7 (Map3k7), mitogen-activated protein kinase kinase kinase 7 (MAP3K7), mitogen-activated protein kinase kinase kinase 7 (Map3k7), B430101B05, C87327, MEKK7, si:ch211-225h9.1, Tak1, TAK1, TGF1a, zgc:110612Protein level used designations for MAP3K7
- mitogen-activated protein kinase kinase kinase 7
- tak1
- TGF-beta-activated kinase TAK1
- TGF-beta activated kinase 1
- TGF-beta-activated kinase 1
- transforming growth factor-beta-activated kinase 1
- mitogen activated protein kinase kinase kinase 7
- transforming growth factor beta-activated kinase 1
Vous êtes ici:
