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MAT1A Produits

(Methionine Adenosyltransferase I, alpha (MAT1A))

Catégories

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008].

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Catégories MAT1A en vedette

MAT1A Anticorps

High quality antibodies with extensive validation data.

MAT1A Kits ELISA

Reliable ELISA kits for a wide range of species.

MAT1A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MAT1A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
N° du produit ABIN517744
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
N° du produit ABIN656632
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
N° du produit ABIN6263141
Quantité 100 μL
Fiche technique Fiche technique

MAT1A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968589
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968588
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968587
Quantité 96 tests
Fiche technique Fiche technique

MAT1A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123931
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310434
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310436
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MAT1A

Fling, Doskey, Fader, Nault, Zacharewski: "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice." dans: Scientific reports, Vol. 10, Issue 1, pp. 14831, (2021) (PubMed).

Kang, Kim, Goo, Jeong, An, Hwang: "Unraveling the role of quorum sensing-dependent metabolic homeostasis of the activated methyl cycle in a cooperative population of Burkholderia glumae." dans: Scientific reports, Vol. 9, Issue 1, pp. 11038, (2019) (PubMed).

Song, Li, Wang, Du, Yang: "DMBA acts on cumulus cells to desynchronize nuclear and cytoplasmic maturation of pig oocytes." dans: Scientific reports, Vol. 7, Issue 1, pp. 1687, (2018) (PubMed).

Jiang, Hurt, Breen, Stabler, Allen, Orlicky, Maclean: "Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap." dans: Biology open, Vol. 4, Issue 9, pp. 1154-62, (2015) (PubMed).

Bing, Zhu, Yu, Li, Liu, Li, Wang, Qi, Guo, Yuan, He, Liu, Liu: "Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells." dans: The Journal of biological chemistry, Vol. 289, Issue 47, pp. 32639-55, (2014) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Geillinger, Rathmann, Köhrle, Fiamoncini, Daniel, Kipp: "Hepatic metabolite profiles in mice with a suboptimal selenium status." dans: The Journal of nutritional biochemistry, Vol. 25, Issue 9, pp. 914-22, (2014) (PubMed).

Cheng, Zhou, Li, Li, Li, Li, Lu: "Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma." dans: Acta pharmacologica Sinica, Vol. 34, Issue 7, pp. 951-9, (2013) (PubMed).

Yang, Cho, Li, Peng, Ko, Mato, Lu: "MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma." dans: The Journal of clinical investigation, Vol. 123, Issue 1, pp. 285-98, (2013) (PubMed).

Guo, Liu, Zhong, Wang, Wang, Xia: "Cyanidin-3-O-?-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells." dans: Lipids in health and disease, Vol. 11, pp. 10, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à MAT1A

methionine adenosyltransferase 1A (MAT1A), methionine adenosyltransferase 1A (Mat1a), methionine adenosyltransferase I, alpha (Mat1a), methionine adenosyltransferase I, alpha (mat1a), AdoMet, AI046368, Ams, MAT, MATA1, SADE, SAMS, SAMS1, SAS, wu:fi35e01, zgc:55442

Protein level used designations for MAT1A

  • MAT 1
  • MAT-I/III
  • S-adenosylmethionine synthase isoform type-1
  • S-adenosylmethionine synthetase isoform type-1
  • adoMet synthase 1
  • adoMet synthetase 1
  • methionine adenosyltransferase 1
  • methionine adenosyltransferase I/III
  • S - adenosylmethionine synthetase
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