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MAT1A Protein (AA 1-395) (His tag)

MAT1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667767
  • Antigène Voir toutes MAT1A Protéines
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-395
    Origine
    • 5
    • 3
    • 3
    • 1
    Humain
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette MAT1A protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    MAT1A, 1-395aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product MAT1A Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M NaCl, 10% glycerol
    Stock
    4 °C
  • Antigène
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    Autre désignation
    MAT1A (MAT1A Produits)
    Synonymes
    MAT Protein, MATA1 Protein, SAMS Protein, SAMS1 Protein, AdoMet Protein, SADE Protein, SAS Protein, AI046368 Protein, Ams Protein, wu:fi35e01 Protein, zgc:55442 Protein, methionine adenosyltransferase 1A Protein, methionine adenosyltransferase I, alpha Protein, MAT1A Protein, Mat1a Protein, mat1a Protein
    Sujet
    MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFkappaB and TNFalpha cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth. Recombinant human MAT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MAT, MATA1, SAMS, SAMS1, methionine adenosyltransferase I alpha, S-adenosylmethionine synthetase, MAT1A,. NCBI no.: NP_000420
    Poids moléculaire
    45.6 kDa (414aa), confirmed by MALDI-TOF.
    Pathways
    Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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