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MELK Produits

(Maternal Embryonic Leucine Zipper Kinase (MELK))
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation (By similarity). Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis.

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Catégories MELK en vedette

MELK Anticorps

High quality antibodies with extensive validation data.

MELK Kits ELISA

Reliable ELISA kits for a wide range of species.

MELK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MELK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, ICC, FACS
Validations
  • (2)
  • (5)
N° du produit ABIN969538
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF, IHC, FACS
Validations
  • (5)
N° du produit ABIN1491623
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, FACS, IF/ICC
Validations
  • (6)
N° du produit ABIN1844288
Quantité 100 μL
Fiche technique Fiche technique

MELK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968452
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957656
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957654
Quantité 96 tests
Fiche technique Fiche technique

MELK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
N° du produit ABIN5569684
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5569614
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310711
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MELK

Li, Chen, Yang, Wang, Wang, Jin, Yang, Chen, Zhou, Luo: "Phillygenin, a MELK Inhibitor, Inhibits Cell Survival and Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells." dans: OncoTargets and therapy, Vol. 13, pp. 2833-2842, (2020) (PubMed).

Hu, Ru, Xiao, Chaturbedi, Hoa, Tian, Zhang, Ke, Yan, Nelson, Li, Gramer, Yu, Siegel, Zhang, Jia, Jadus, Limoli, Linskey, Xing, Zhou: "Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80898, (2013) (PubMed).

Nakano, Joshi, Visnyei, Hu, Watanabe, Lam, Wexler, Saigusa, Nakamura, Laks, Mischel, Viapiano, Kornblum: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." dans: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).

Pickard, Green, Ellis, Caldas, Hedge, Mourtada-Maarabouni, Williams: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." dans: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).

Lin, Park, Nishidate, Nakamura, Katagiri: "Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family." dans: Breast cancer research : BCR, Vol. 9, Issue 1, pp. R17, (2007) (PubMed).

Niesler, Myburgh, Moore: "The changing AMPK expression profile in differentiating mouse skeletal muscle myoblast cells helps confer increasing resistance to apoptosis." dans: Experimental physiology, Vol. 92, Issue 1, pp. 207-17, (2007) (PubMed).

Davezac, Baldin, Blot, Ducommun, Tassan: "Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation." dans: Oncogene, Vol. 21, Issue 50, pp. 7630-41, (2002) (PubMed).

Nagase, Seki, Ishikawa, Tanaka, Nomura: "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1." dans: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 3, Issue 1, pp. 17-24, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à MELK

maternal embryonic leucine zipper kinase (MELK), maternal embryonic leucine zipper kinase (melk), maternal embryonic leucine zipper kinase (cgd5_2270), maternal embryonic leucine zipper kinase (Melk), maternal embryonic leucine zipper kinase L homeolog (melk.L), AI327312, fb71b01, fe01f04, HPK38, MELK, Melk, mKIAA0175, MPK38, wu:fb71b01, wu:fe01f04, xmelk

Protein level used designations for MELK

  • maternal embryonic leucine zipper kinase
  • maternal embryonic leucine zipper kinase-like
  • pEg3 kinase
  • protein kinase Eg3
  • protein kinase PK38
  • tyrosine-protein kinase MELK
  • zMelk
  • Protein kinase Eg3
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