Menin Produits
(Multiple Endocrine Neoplasia 1 (MEN1))
Catégories
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].
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Catégories Menin en vedette
Menin Anticorps
High quality antibodies with extensive validation data.
Menin Kits ELISA
Reliable ELISA kits for a wide range of species.
Menin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Menin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (5)
N° du produit
ABIN2682998
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7443704
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN676343
Quantité
100 μL
Fiche technique
Fiche technique
Menin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1142130
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1142131
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1142132
Quantité
96 tests
Fiche technique
Fiche technique
Menin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310718
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310714
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417234
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Menin
: "MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair." dans: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2635-47, (2013) (PubMed).: "Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation." dans: Glia, Vol. 60, Issue 9, pp. 1427-36, (2012) (PubMed).
: "Genome-wide characterization of menin-dependent H3K4me3 reveals a specific role for menin in the regulation of genes implicated in MEN1-like tumors." dans: PLoS ONE, Vol. 7, Issue 5, pp. e37952, (2012) (PubMed).
: "The negative feedback-loop between the oncomir Mir-24-1 and menin modulates the Men1 tumorigenesis by mimicking the "Knudson's second hit"." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39767, (2012) (PubMed).
: "Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 6, pp. G752-64, (2012) (PubMed).
: "Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity." dans: Neuroscience, Vol. 223, pp. 473-85, (2012) (PubMed).
: "Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1." dans: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 3, pp. E474-83, (2011) (PubMed).
: "Regulation of cyclin B2 expression and cell cycle G2/m transition by menin." dans: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18291-300, (2010) (PubMed).
: "Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice." dans: Endocrinology, Vol. 151, Issue 8, pp. 4024-30, (2010) (PubMed).
: "MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases." dans: Endocrine-related cancer, Vol. 17, Issue 3, pp. 771-83, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à Menin
menin 1 (MEN1), menin 1 (men1), menin 1 L homeolog (men1.L), multiple endocrine neoplasia I (men1), multiple endocrine neoplasia 1 (Men1), menin 1 (Men1), AW045611, MEAI, meai, menin, SCG2, scg2Protein level used designations for Menin
- menin
- multiple endocrine neoplasia protein
- multiple endocrine neoplasia 1
- multiple endocrine neoplasia I
- menin-like
Avez-vous cherché autre chose?
- MEND
- menC
- MEMO1
- Membrane-Spanning 4-Domains, Subfamily A, Member 8
- Membrane transport protein XK
- Membrane Protein, Palmitoylated 2 (MAGUK P55 Subfamily Member 2)
- Membrane IgA
- Membralin
- MELK
- Melittin
- MELC2
- Melatonin Sulfate
- Melatonin Receptor 1B
- Melatonin Receptor 1A
- Melatonin Receptor
- Melatonin
- Melanophilin
- Melanoma Marker
- Melanoma Associated Antigen
- Melanoma Antigen Family D, 4B
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