Metabotropic Glutamate Receptor 5 Produits
(Glutamate Receptor, Metabotropic 5 (GRM5))
Catégories
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009].
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Catégories Metabotropic Glutamate Receptor 5 en vedette
Metabotropic Glutamate Receptor 5 Anticorps
High quality antibodies with extensive validation data.
Metabotropic Glutamate Receptor 5 Kits ELISA
Reliable ELISA kits for a wide range of species.
Metabotropic Glutamate Receptor 5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Metabotropic Glutamate Receptor 5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, ELISA, ICC
Validations
- (6)
N° du produit
ABIN5611178
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC, LCI
Validations
- (5)
N° du produit
ABIN7043250
Quantité
25 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
N° du produit
ABIN516205
Quantité
100 μg
Fiche technique
Fiche technique
Metabotropic Glutamate Receptor 5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967067
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1743303
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Validations
N° du produit
ABIN1774208
Quantité
96 tests
Fiche technique
Fiche technique
Metabotropic Glutamate Receptor 5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355782
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Mammalian Cells
Validations
N° du produit
ABIN7538304
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Metabotropic Glutamate Receptor 5
: "Autism-associated Shank3 mutations alter mGluR expression and mGluR-dependent but not NMDA receptor-dependent long-term depression." dans: Synapse (New York, N.Y.), Vol. 73, Issue 8, pp. e22097, (2019) (PubMed).: "Synaptic integration of newly generated neurons in rat dissociated hippocampal cultures." dans: Molecular and cellular neurosciences, Vol. 47, Issue 3, pp. 203-14, (2011) (PubMed).
: "The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption." dans: Nature medicine, Vol. 11, Issue 1, pp. 35-42, (2005) (PubMed).
: "Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation." dans: The Journal of biological chemistry, Vol. 279, Issue 32, pp. 33352-8, (2004) (PubMed).
: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." dans: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).
: "Differential expression of mGluR5 in human lumbosacral motoneurons." dans: Neuroreport, Vol. 15, Issue 2, pp. 271-3, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à Metabotropic Glutamate Receptor 5
glutamate receptor, metabotropic 5 (GRM5), glutamate metabotropic receptor 5 (GRM5), glutamate metabotropic receptor 5 (Grm5), glutamate receptor, metabotropic 5 (Grm5), 6430542K11Rik, AI850523, Glu5R, GPRC1E, Gprc1e, mGlu5, MGLUR5, mGluR5, mGlur5, mGluR5bProtein level used designations for Metabotropic Glutamate Receptor 5
- metabotropic glutamate receptor 5
- metabotropic glutamate receptor 5 variant F
- metabotropic glutamate receptor 5 variant G
- metabotropic glutamate receptor 5 variant H
- metabotropic glutamate receptor (mGluR5)
- metabotropic glutamate receptor 5b
- G protein coupled receptor, family C, group 1, member E
- G protein-coupled receptor GRM5
- G protein-coupled receptor, family C, group 1, member E
- metabotropic glutamate receptor subtype 5b
- metabotropic glutamate receptor type 5
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