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NEDD9 Produits

(Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Catégories

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Catégories NEDD9 en vedette

NEDD9 Anticorps

High quality antibodies with extensive validation data.

NEDD9 Kits ELISA

Reliable ELISA kits for a wide range of species.

NEDD9 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NEDD9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (9)
N° du produit ABIN3023331
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (3)
N° du produit ABIN129518
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (3)
N° du produit ABIN561951
Quantité 50 μg
Fiche technique Fiche technique

NEDD9 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968848
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1131949
Quantité 96 tests
Fiche technique Fiche technique

NEDD9 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312334
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312332
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3090359
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NEDD9

Zhou, Xu, Shen, Liu, Chen, Cai: "Overexpression of NEDD9 promotes cell invasion and metastasis in hepatocellular carcinoma." dans: Clinics and research in hepatology and gastroenterology, Vol. 41, Issue 6, pp. 677-686, (2018) (PubMed).

Santos, Blair, Kumari, Cammer, Iskratsch, Herbin, Alexandropoulos, Dustin, Sheetz: "Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability." dans: Immunology and cell biology, Vol. 94, Issue 10, pp. 981-993, (2016) (PubMed).

Liu, Wang, Zhao, Zhu, Yin, Wei, Wu, Cheng, Wang, Ni, Wang, Cao, Huang, Cai: "NEDD9 overexpression correlates with poor prognosis in gastric cancer." dans: Tumour biology, Vol. 35, Issue 7, pp. 6351-6, (2014) (PubMed).

Tomkiewicz, Herry, Bui, Métayer, Bourdeloux, Barouki, Coumoul: "The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway." dans: Oncogene, Vol. 32, Issue 14, pp. 1811-20, (2013) (PubMed).

Sima, Cheng, Ye, Ma, Xie, Lü: "The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC." dans: PLoS ONE, Vol. 8, Issue 9, pp. e74594, (2013) (PubMed).

Zhong, Baquiran, Bonakdar, Lees, Ching, Pugacheva, Fabry, ONeill: "NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration." dans: PLoS ONE, Vol. 7, Issue 4, pp. e35058, (2012) (PubMed).

Lim, Chen, Tomar, Miller, Yoo, Schlaepfer: "Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation." dans: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21526-36, (2010) (PubMed).

Li, Grupe, Rowland, Holmans, Segurado, Abraham, Jones, Catanese, Ross, Mayo, Martinez, Hollingworth, Goate, Cairns, Racette, Perlmutter, ODonovan, Morris, Brayne, Rubinsztein, Lovestone, Thal, Owen et al.: "Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. ..." dans: Human molecular genetics, Vol. 17, Issue 5, pp. 759-67, (2008) (PubMed).

Kim, Gans, Nogueira, Wang, Paik, Feng, Brennan, Hahn, Cordon-Cardo, Wagner, Flotte, Duncan, Granter, Chin: "Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene." dans: Cell, Vol. 125, Issue 7, pp. 1269-81, (2006) (PubMed).

Regelmann, Danzl, Wanjalla, Alexandropoulos: "The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking." dans: Immunity, Vol. 25, Issue 6, pp. 907-18, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à NEDD9

neural precursor cell expressed, developmentally down-regulated 9 (NEDD9), neural precursor cell expressed, developmentally down-regulated 9 (Nedd9), neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), CAS-L, Cas-L, CAS2, CASL, CasL, CASS2, E230025G09Rik, HEF1, NEDD9

Protein level used designations for NEDD9

  • neural precursor cell expressed, developmentally down-regulated 9
  • enhancer of filamentation 1 homolog
  • Cas scaffolding protein family member 2
  • Crk-associated substrate related protein Cas-L
  • Enhancer of filamentation 1 p55
  • cas-like docking
  • enhancer of filamentation 1
  • neural precursor cell expressed developmentally down-regulated protein 9
  • p130Cas-related protein
  • renal carcinoma antigen NY-REN-12
  • neural precursor cell expressed, developmentally down-regulated gene 9
  • CRK-associated substrate-related protein
  • Crk-associated substrate lymphocyte-specific protein
  • NEDD-9
  • mEF1
  • p105
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