NEDD9 anticorps (AA 82-398)

N° du produit ABIN7278755

Détail du produit anti-NEDD9 anticorps

Antigène: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Épitope: AA 82-398

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NEDD9 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Does not recognize p130 Cas. Not tested on Sin1. This antibody mostly detects HEF1 localized at the focal adhesion sites

Purification: Protein G

Immunogène: Fusion protein, corresponding to amino acids 82-398 of Human HEF1.

Clone: 2G9

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1/2000 - 1/6000. Predicted molecular weight: 93 kDa. IP: 1/1000. ICC/IF: Use at an assay dependent dilution. PubMed: 19376971 IHC-Fr: Use at an assay dependent dilution. PubMed: 19464348 Flow Cyt: Use 1 μg for 106 cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody containing PBS 0.1 % sodium azide,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Références pour anticorps anti-NEDD9 (ABIN7278755)

Tomkiewicz, Herry, Bui, Métayer, Bourdeloux, Barouki, Coumoul: "The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway." dans: Oncogene, Vol. 32, Issue 14, pp. 1811-20, (2013) (PubMed).

Zhong, Baquiran, Bonakdar, Lees, Ching, Pugacheva, Fabry, ONeill: "NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration." dans: PLoS ONE, Vol. 7, Issue 4, pp. e35058, (2012) (PubMed).

ONeill, Golemis: "Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics." dans: Molecular and cellular biology, Vol. 21, Issue 15, pp. 5094-108, (2001) (PubMed).

Détails sur NEDD9

Antigène: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Autre désignation: HEF1 (NEDD9 Produits)

Synonymes: anticorps NEDD9, anticorps CAS-L, anticorps CAS2, anticorps CASL, anticorps CASS2, anticorps HEF1, anticorps Cas-L, anticorps CasL, anticorps E230025G09Rik, anticorps neural precursor cell expressed, developmentally down-regulated 9, anticorps neural precursor cell expressed, developmentally down-regulated gene 9, anticorps NEDD9, anticorps Nedd9

Sujet: Synonyms:
CAS L antibody,Cas like docking antibody,CASL antibody,Crk associated substrate related proteinantibody,dJ49G10.2 antibody,dJ761I2.1 antibody,Enhancer of filamentation 1 antibody,HEF 1 antibody,NEDD 9antibody,NEDD9 antibody,NEDD9 protein antibody,Neural cell expressed developmentally down regulated 9antibody,Neural precursor cell expressed developmentally down regulated 9 antibody,NY REN 12 antigenantibody,p105 antibody,Protein NEDD9 antibody

ID gène: 4739, 18003, 291044

OMIM: 602265

UniProt: O35177