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Human Monoclonal ESR2 Primary Antibody pour ChIP, DB - ABIN152350
Kuiper, Carlsson, Grandien, Enmark, Haeggblad, Nilsson, Gustafsson: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. dans Endocrinology 1997
Show all 74 Pubmed References
Human Monoclonal ESR2 Primary Antibody pour ChIP, ICC - ABIN152348
Bianco, Perry, Smith, Templeton, Montano: Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. dans Molecular endocrinology (Baltimore, Md.) 2003
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Human Monoclonal ESR2 Primary Antibody pour ChIP, IP - ABIN445498
Burakov, Crofts, Chang, Freedman: Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. dans The Journal of biological chemistry 2002
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Human Monoclonal ESR2 Primary Antibody pour IHC, WB - ABIN152349
Fuchsjäger-Mayrl, Nepp, Schneeberger, Sator, Dietrich, Wedrich, Huber, Tschugguel: Identification of estrogen and progesterone receptor mRNA expression in the conjunctiva of premenopausal women. dans Investigative ophthalmology & visual science 2002
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Human Monoclonal ESR2 Primary Antibody pour IHC (p) - ABIN2473530
Howard: Studies on urinary stone formation: a saga of clinical investigation. dans The Johns Hopkins medical journal 1977
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Human Monoclonal ESR2 Primary Antibody pour IHC (p) - ABIN2473529
Saunders, Millar, Macpherson, Irvine, Groome, Evans, Sharpe, Scobie: ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis. dans The Journal of clinical endocrinology and metabolism 2002
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Human Polyclonal ESR2 Primary Antibody pour FACS, IF (p) - ABIN725210
Fang, Wu, Huang: Raloxifene upregulated mesangial cell MMP-2 activity via ER-? through transcriptional regulation. dans Cell biochemistry and biophysics 2013
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Human Polyclonal ESR2 Primary Antibody pour WB - ABIN1881321
Fang, Lu, Wang, Wu, Li, Zhang, Pan, Wan: Prognostic impact of ERβ and MMP7 expression on overall survival in colon cancer. dans Tumour biology 2010
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Human Polyclonal ESR2 Primary Antibody pour WB - ABIN1881322
Hayes, Skaar, Rae, Henry, Nguyen, Stearns, Li, Philips, Desta, Flockhart: Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results. dans Clinical pharmacology and therapeutics 2010
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We found higher nuclear (n)ERalpha (Montrer ESR1 Anticorps) and nERbeta5 and lower cytoplasmic (c)ERalpha (Montrer ESR1 Anticorps) expression in advanced ovarian cancers. Lower ERbeta1 expression was also detected in high grade cancers. Loss of nERalpha and cERbeta2 expression were observed in clear cell histological subtypes. Higher nERbeta5 and lower cERbeta5 expression were associated with serous/clear cell subtypes, poor disease-free and overall survival.
We found little overall difference in the DNA methylation (Montrer HELLS Anticorps) of the ESR2 5'-flanking region in individuals with autism compared with normal individuals.
our data reveal a novel mechanism for ERbeta's anti-proliferative and pro-apoptotic effects in breast cancer cells involving p53 (Montrer TP53 Anticorps) and epigenetic changes in histone methylation that underlie gene regulation of these cellular activities.
loss of ERbeta function acts in collaboration with p53 (Montrer TP53 Anticorps) inactivation to induce early onset of mammary tumors with spindle cell morphology and more basal-like characteristics.
Low levels of ESR2 is associated with metastasis in triple-negative breast cancer.
Findings from the systematic review and meta-analysis suggest that rs1256120 of ESR2 is unlikely to be a predisposing or disease-modifying genetic risk factor for adolescent idiopathic scoliosis.
High concentrations of DINCH urinary metabolites activate human ESR2 receptors.
Tumor ERbeta1 expression was available for 911 breast cancer patients and was not associated with ESR2 genotypes. High tumor ERbeta1 expression is a marker of good prognosis in breast cancer, especially among chemotherapy-treated patients, but not in endocrine therapy-treated patients.
the association between four ESR1 (Montrer ESR1 Anticorps) gene variants, and six ESR2 single nucleotide polymorphisms and breast cancer risk in Tunisian women
Targeting ERbeta with selective agonists might affect Hodgkins lymphoma cell proliferation and tumor growth via a mechanism that brings into play DRAM2 (Montrer DRAM2 Anticorps)-dependent autophagic cascade.
Comprehensive genetic analysis for differential functions of esr1, esr2a, and esr2b in fish reproduction.
although esr2b mutant fish showed unaltered antibacterial responses, they were unable to mount an effective antiviral response upon viral challenge.
This study revealed similar patterns of transcript abundance across reproductive morphs for ERbeta1, ERbeta2, ERalpha (Montrer ESR1 Anticorps), and aromatase in the forebrain and saccule.
It was concluded that morpholino (MO) oligonucleotid technology in zebrafish embryos is an good approach for investigating the interplay of estrogen receptor (Montrer ESR1 Anticorps) subtypes in a true physiological context.
during embryogenesis two of the three 17beta-estradiol receptor genes, esr1 and esr2b are expressed, and in presence of ligand the mRNA levels of these two genes increase
Data show that temperature and photoperiod significantly influence the transcription of the estrogen-responsive genes, Vtg1, Vtg2 (Montrer VTG Anticorps), ER alpha (Montrer ESR1 Anticorps) and ER beta after a 21-day exposure to endocrine-disrupting chemicals.
Cloning of the cDNAs corresponding to three oestrogen receptors (esr1 (Montrer ESR1 Anticorps), ERalpha (Montrer ESR1 Anticorps); esr2b, ERbeta1; and esr2a (Montrer ESR1 Anticorps), ERbeta2 ).
Data show that the hepatic expression of estrogen receptor alpha (Montrer ESR1 Anticorps), beta1 and beta2 genes responds differently to estradiol.
genistein binds and activates the three zebrafish estrogen receptors ERalpha (Montrer ESR1 Anticorps), ERbeta-A and ERbeta-B (Montrer ESR1 Anticorps) and induces apoptosis in an ER-independent manner
The mRNA expression of ER-alpha (Montrer ESR1 Anticorps) and ER-beta in the hypothalamus of developing male and female bovines, is reported.
ER-alpha (Montrer ESR1 Anticorps) is detected predominantly in the soma whereas ER-beta is only present in the nucleus of a few cells in the frontal cortex.
fetal ovary of cattle has the steroidogenic enzyme aromatase (Montrer CYP19A1 Anticorps) to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary
there are different levels of ERalpha (Montrer ESR1 Anticorps), ERbeta and PR in bovine oviducts at different cycle stages in vivo
The expression of estrogen and progesterone receptors in ovarian follicular structures from cows with cystic ovarian disease (COD (Montrer SNRPB Anticorps)) and a comparison of these with normal ovarian structures are reported.
These data indicate that PGF2alpha, TNFalpha (Montrer TNF Anticorps) and IFNgamma regulate ERalpha (Montrer ESR1 Anticorps) and ERbeta mRNA expressions in bovine luteal cells.
Roles of IGF-I (Montrer IGF1 Anticorps) and the estrogen, androgen and IGF-I (Montrer IGF1 Anticorps) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
an 17b-estradiol-induced increase in the proliferation of rhesus retinal capillary endothelial cells may be mediated by the action of ERb.
Estradiol can weakly modulate the motility and this effect is strictly associated with GPER (Montrer GPER Anticorps) and not with ESR1 (Montrer ESR1 Anticorps) and ESR2. The subcellular localization of GPER (Montrer GPER Anticorps) in the neck on stallion sperm is coherent with this effect.
The presence of a single isoform of ESR1 (Montrer ESR1 Anticorps) (66kDa (Montrer SF3A2 Anticorps)) and ESR2 (61kDa) was found by Western-blot analysis in samples from seven stallions and the expression of the seven transmembrane estradiol binding receptor GPER (Montrer GPER Anticorps) in colt testis.
expression of estrogen receptor alpha (Montrer ESR1 Anticorps) and beta and progesterone receptor (Montrer PGR Anticorps) in equine microplacentomes gives evidence for a role of placental steroids as regulators of placental function
There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found.
steroid hormones, AhR (Montrer AHR Anticorps) and estrogen receptor beta are affected by TCDD and genistein in granulosa cells of medium porcine follicles
Results suggest that expression levels of protease activated receptors 1 and 2 (PAR-1 (Montrer F2R Anticorps) and PAR-2 (Montrer F2RL1 Anticorps)) associate with breast cancer outcome in an estrogen receptor (ER (Montrer ESR1 Anticorps))-dependent manner.
results might shed new light on the roles of estrogen receptor (Montrer ESR1 Anticorps) 2(ESR2) in spermatogenesis as candidate for boar fertility
Downregulation of the ERs, particularly ERalpha (Montrer ESR1 Anticorps) in the myometrium and endometrial stroma, might be a relevant mechanism in the antagonism of estrogenic effects by dihydrotestosterone in the pig uterus.
the results of the present study suggest the involvement of estrogen receptor beta in estrogen modulation of pig epididymal function
ERbeta mRNA was found only in Sertoli cells in the testis.
positive staining for ERalpha (Montrer ESR1 Anticorps) in the nuclei of skeletal muscle cells, while the ERbeta stain showed positive signals in nuclei and cytoplasm of skeletal myofibers and myoblasts derived from satellite cells
ESR2 gene polymorphisms are associated with litter size.
The objective of this study was to search for polymorphisms in the coding region of the estrogen receptors 1 and 2 (ESR1 (Montrer ESR1 Anticorps) and ESR2) and to analyze the effects of these variants and the well known intronic ESR1 (Montrer ESR1 Anticorps) PvuII polymorphism on litter size.
Study found that estrogen receptor beta (ERbeta) was expressed in the motoneurons of lumbar ventral horn. ERalpha (Montrer ESR1 Anticorps) and ERbeta were mainly localized in the nuclei of motoneurons with less immunoreactivity in the cytoplasm.
Data suggest that expression of Usp19 (Montrer USP19 Anticorps) in skeletal muscle can be regulated by dietary factors; here, supplementation with phytoestrogen daidzein down-regulates Usp19 (Montrer USP19 Anticorps) expression via Esrb signaling and increases skeletal muscle mass. (Usp19 (Montrer USP19 Anticorps) = ubiquitin-specific peptidase 19 (Montrer USP19 Anticorps); Esrb = estrogen receptor beta)
The role of ERbeta in opposing AR signaling, proliferation, and inflammation suggests that ERbeta-selective agonists may be used to prevent progression of prostate cancer, prevent fibrosis and development of benign prostatic hyperplasia, and treat prostatitis.
Data suggest that one alternative splicing variant of Esr2 is "super-activated" by xenoestrogens; here, samples isolated from soil around a landfill site in the United Kingdom appear to contain xenoestrogens that induce cholangitis.
The administration of ICI182,780, which is an agonist of G-protein coupled estrogen receptor (Montrer ESR1 Anticorps) (GPER (Montrer GPER Anticorps)) and an antagonist of ERa and ERb, did not result in protection; however, ICI182,780 significantly blocked EDC-mediated cardioprotection, indicating participation of ERalpha (Montrer ESR1 Anticorps) and/or ERbeta
ERbeta might be the target protein of arctigenin responsible for inhibition of mTORC1 activation and resultant prevention of Th17 cell differentiation and colitis development.
Taken together, the above results clearly demonstrated an mTORC2 (Montrer CRTC2 Anticorps)-dependent regulation of actin polymerization that contributed to the effects of ERalpha (Montrer ESR1 Anticorps) and ERbeta on spatial learning, which may provide a novel target for the prevention and treatment of E2-related dementia in the aged population
Results provide evidence that ERbeta prevents cardiac fibroblasts to undergo fibrosis development.
Increased DNA methylation (Montrer HELLS Anticorps) accompanied this pattern, particularly at CpG dinucleotides located within binding or flanking regions for the transcriptional regulator CCCTC-binding factor (Montrer CTCF Anticorps) of ESR1 (Montrer ESR1 Anticorps) and ESR2, consistent with sustained transcriptional activation of ERa and ERb
These data highlight a new role for ER-beta in adipose biology and its potential to be a safer alternative peripheral therapeutic target for obesity.
cloned three ER subtypes (ERalpha (Montrer ESR1 Anticorps), ERbeta1, and ERbeta2), and examined their developmental expression in the gonads of females and males during embryonic and larval development
The expression of androgen receptors, estrogen receptor beta, and bone morphogenetic protein 2b (Montrer BMP4 Anticorps) in male and female Japanese and Thai medaka are reported.
The main functional structure domains of the ESR2 in a Jining Gray female goat have been described.
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
estrogen nuclear receptor beta variant a
, estrogen nuclear receptor beta variant b
, estrogen receptor beta
, estrogen receptor beta 4
, nuclear receptor subfamily 3 group A member 2
, estrogen receptor beta1
, estrogen receptor beta 2
, estrogen receptor 2 (ER beta)
, estradiol receptor beta
, steroid receptor
, ER beta
, oestrogen receptor beta
, estrogen receptor 2 beta
, Nuclear receptor subfamily 3 group A member 2
, estrogen receptor beta-like
, estrogen receptor 2 (beta)