Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Produits
(Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
Catégories
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009].
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Catégories Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) en vedette
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Anticorps
High quality antibodies with extensive validation data.
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Kits ELISA
Reliable ELISA kits for a wide range of species.
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC
Validations
- (5)
N° du produit
ABIN184751
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN518586
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (4)
N° du produit
ABIN7269401
Quantité
100 μL
Fiche technique
Fiche technique
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969386
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1148326
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1148327
Quantité
96 tests
Fiche technique
Fiche technique
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313891
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313893
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3093548
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)
: "Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex." dans: Journal of proteome research, Vol. 12, Issue 11, pp. 5233-45, (2013) (PubMed).: "Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer." dans: Lung cancer (Amsterdam, Netherlands), Vol. 77, Issue 3, pp. 585-92, (2012) (PubMed).
: "Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]." dans: American journal of human genetics, Vol. 88, Issue 5, pp. 536-47, (2011) (PubMed).
: "Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning." dans: Journal of cell science, Vol. 123, Issue Pt 2, pp. 202-12, (2010) (PubMed).
: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).
: "Neuronal migration in developmental disorders." dans: Journal of child neurology, Vol. 20, Issue 4, pp. 280-6, (2005) (PubMed).
: "APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment." dans: Molecular biology of the cell, Vol. 16, Issue 10, pp. 4609-22, (2005) (PubMed).
: "LIS2, gene and pseudogene, homologous to LIS1 (lissencephaly 1), located on the short and long arms of chromosome 2." dans: Genomics, Vol. 30, Issue 2, pp. 251-6, (1996) (PubMed).
: "Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]." dans: Nature, Vol. 370, Issue 6486, pp. 216-8, (1994) (PubMed).
: "Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats." dans: Nature, Vol. 364, Issue 6439, pp. 717-21, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)
platelet activating factor acetylhydrolase 1b regulatory subunit 1 (PAFAH1B1), platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 (Pafah1b1), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (Pafah1b1), platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog (pafah1b1.L), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a (pafah1b1a), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b (pafah1b1b), platelet activating factor acetylhydrolase 1b regulatory subunit 1 (Pafah1b1), LIS-1, LIS1, Lis1, Lis1a, LIS2, lis2, MDCR, mdcr, MDS, mds, Mdsh, MMS10-U, Ms10u, PAFAH, pafah, pafah1b1-b, Pafaha, PAFAHAProtein level used designations for Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)
- LIS-1
- PAF acetylhydrolase 45 kDa subunit
- PAF-AH 45 kDa subunit
- PAF-AH alpha
- PAFAH alpha
- lissencephaly 1 protein
- lissencephaly-1 protein
- platelet-activating factor acetylhydrolase IB subunit alpha
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
- platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
- platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
- platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
- PAF-AH beta
- platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta)
- platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
- LIS1
- lissencephaly-1 homolog
- lissencephaly-1 homolog B
- chLIS1
- platelet-activating factor acetylhydrolase Ib-alpha subunit
- Miller-Dieker syndrome chromosome region
- Lissencephaly-1 protein
- platelet-activating factor acetylhydrolase isoform Ib alpha subunit
- lis1b
- lissencephaly-1 homolog A
- platelet-activating factor acetylhydrolase IB subunit alpha a
- platelet-activating factor acetylhydrolase IB subunit alpha b
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