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P4HTM Produits

(Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Catégories

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories P4HTM en vedette

P4HTM Anticorps

High quality antibodies with extensive validation data.

P4HTM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

P4HTM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN527161
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Bat, Cow, Dog, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
N° du produit ABIN6744213
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
N° du produit ABIN6741725
Quantité 100 μL
Fiche technique Fiche technique

P4HTM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313840
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3085333
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3124638
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits P4HTM

Klotzsche-von Ameln, Prade, Grosser, Kettelhake, Rezaei, Chavakis, Flamme, Wielockx, Breier: "PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α." dans: Molecular cancer research : MCR, Vol. 11, Issue 11, pp. 1337-48, (2013) (PubMed).

Henze, Riedel, Diem, Wenner, Flamme, Pouyseggur, Plate, Acker: "Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors." dans: Cancer research, Vol. 70, Issue 1, pp. 357-66, (2010) (PubMed).

Khan, Michalopoulos, Stolz: "Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation." dans: The American journal of pathology, Vol. 169, Issue 4, pp. 1251-69, (2006) (PubMed).

Maxwell, Ratcliffe: "Oxygen sensors and angiogenesis." dans: Seminars in cell & developmental biology, Vol. 13, Issue 1, pp. 29-37, (2002) (PubMed).

Ivan, Haberberger, Gervasi, Michelson, Günzler, Kondo, Yang, Sorokina, Conaway, Conaway, Kaelin: "Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 21, pp. 13459-64, (2002) (PubMed).

Bruick, McKnight: "A conserved family of prolyl-4-hydroxylases that modify HIF." dans: Science (New York, N.Y.), Vol. 294, Issue 5545, pp. 1337-40, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à P4HTM

prolyl 4-hydroxylase, transmembrane (P4htm), prolyl 4-hydroxylase, transmembrane (P4HTM), prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4htm), shisa family member 5 (SHISA5), 4933406E20Rik, AI853847, BB128974, EGLN4, HIFPH4, P4H-TM, Ph-4, PH-4, PH4, PHD4, RGD1311848

Protein level used designations for P4HTM

  • hypoxia-inducible factor prolyl 4-hydroxylase
  • transmembrane prolyl 4-hydroxylase
  • HIF-PH4
  • HIF-prolyl hydroxylase 4
  • HPH-4
  • P4H with transmembrane domain
  • Prolyl hydroxlase domain-containing 4
  • hypoxia inducible factor prolyl 4 hydroxylase
  • hypoxia-inducible factor prolyl hydroxylase 4
  • proline 4-hydroxylase
  • P4H-TM
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