p300 Produits
(E1A Binding Protein P300 (EP300))
Catégories
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008].
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Catégories p300 en vedette
p300 Anticorps
High quality antibodies with extensive validation data.
p300 Kits ELISA
Reliable ELISA kits for a wide range of species.
p300 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
p300 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
N° du produit
ABIN6140193
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (1)
- (4)
N° du produit
ABIN560748
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (6)
N° du produit
ABIN3042372
Quantité
100 μg
Fiche technique
Fiche technique
p300 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6955487
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955486
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955488
Quantité
96 tests
Fiche technique
Fiche technique
p300 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352865
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (1)
- (1)
N° du produit
ABIN2720219
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN2669637
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits p300
: "Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions." dans: Molecular cell, Vol. 71, Issue 5, pp. 718-732.e9, (2019) (PubMed).: "MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes." dans: Molecular cell, Vol. 70, Issue 5, pp. 825-841.e6, (2018) (PubMed).
: "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway." dans: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018) (PubMed).
: "miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy." dans: Diabetes, Vol. 65, Issue 3, pp. 768-79, (2016) (PubMed).
: "Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions." dans: Scientific reports, Vol. 6, pp. 29311, (2016) (PubMed).
: "PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia." dans: Oncotarget, Vol. 7, Issue 6, pp. 6379-97, (2016) (PubMed).
: "An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility." dans: Biological psychiatry, Vol. 80, Issue 12, pp. 943-954, (2016) (PubMed).
: "A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer." dans: Oncotarget, Vol. 7, Issue 6, pp. 7253-67, (2016) (PubMed).
: "The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway." dans: Biochemical pharmacology, Vol. 101, pp. 100-11, (2016) (PubMed).
: "Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0120352, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à p300
E1A binding protein p300 (EP300), histone acetyltransferase p300 (LOC446056), E1A binding protein p300 (ep300), E1A binding protein p300 (Ep300), A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2Protein level used designations for p300
- histone acetyltransferase p300
- histone acetyltransferase
- E1A binding protein p300
- histone acetyltransferase p300-like
- E1A-associated protein p300
- E1A-binding protein, 300kD
- p300 HAT
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