PCBP1 Produits
(Poly(rC) Binding Protein 1 (PCBP1))
Catégories
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008].
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Catégories PCBP1 en vedette
PCBP1 Anticorps
High quality antibodies with extensive validation data.
PCBP1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PCBP1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PCBP1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (7)
N° du produit
ABIN2778971
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
N° du produit
ABIN518653
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (4)
N° du produit
ABIN6145277
Quantité
100 μL
Fiche technique
Fiche technique
PCBP1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969446
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1148571
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Validations
N° du produit
ABIN1148569
Quantité
96 tests
Fiche technique
Fiche technique
PCBP1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124508
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314125
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314127
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PCBP1
: "PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27." dans: Molecular cancer research : MCR, Vol. 14, Issue 7, pp. 634-46, (2016) (PubMed).: "Establishing an in vivo p48ZnF bioluminescence mouse brain imaging model." dans: Neuroscience letters, Vol. 542, pp. 97-101, (2013) (PubMed).
: "Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells." dans: Genome research, Vol. 22, Issue 8, pp. 1457-67, (2012) (PubMed).
: "PCBP1 is required for maintenance of the transcriptionally silent state in fully grown mouse oocytes." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 15, pp. 2833-42, (2012) (PubMed).
: "Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest." dans: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9039-49, (2009) (PubMed).
: "A cytosolic iron chaperone that delivers iron to ferritin." dans: Science (New York, N.Y.), Vol. 320, Issue 5880, pp. 1207-10, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à PCBP1
poly(rC) binding protein 1 (PCBP1), poly(rC) binding protein 1 L homeolog (pcbp1.L), poly(rC)-binding protein 1 (LOC100388387), poly(rC) binding protein 1 (Pcbp1), alphaCP-1, hnRNP-E1, hnRNP-X, hnRNP E1, HNRPE1, HNRPX, PCBP1, RGD1561319, WBP17, [a]CP-1Protein level used designations for PCBP1
- poly(rC) binding protein 1
- poly(rC)-binding protein 1-like
- alpha-CP1
- heterogeneous nuclear ribonucleoprotein E1
- heterogenous nuclear ribonucleoprotein E1
- heterogenous nuclear ribonucleoprotein X
- nucleic acid-binding protein SUB2.3
- poly(rC)-binding protein 1
- hnRNP-E1 protein
- hnRNP E1
- hnRNP-E1
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