Ataxin 7-Like 3 (ATXN7L3) (Middle Region) Peptide
ATXN7L3
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits ATXN7L3
- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- MNKSESDQED NDDINDNDWS YGSEKKAKKR KSDKLWYLPF QNPNSPRRSK
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ATXN7L3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
- Synonymes
- E030022H21Rik Peptide, si:busm1-180g5.4 Peptide, si:dz180g5.4 Peptide, wu:fj12f07 Peptide, zgc:136438 Peptide, zgc:158566 Peptide, ataxin 7 like 3 Peptide, ataxin 7-like 3 Peptide, ATXN7L3 Peptide, Atxn7l3 Peptide, atxn7l3 Peptide
- Sujet
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ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Alias Symbols: DKFZp761G2113
Protein Size: 354 - Poids moléculaire
- 38 kDa
- ID gène
- 56970
- NCBI Accession
- NM_020218, NP_064603
- UniProt
- Q14CW9
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