RAD23 Homolog B (RAD23B) (Middle Region) Peptide
RAD23B
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits RAD23B
- RAD23B (RAD23 Homolog B (RAD23B))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- PASITPASAT ASSEPAPASA AKQEKPAEKP AETPVATSPT ATDSTSGDSS
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- RAD23B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- RAD23B (RAD23 Homolog B (RAD23B))
- Synonymes
- HHR23B Peptide, HR23B Peptide, P58 Peptide, 0610007D13Rik Peptide, AV001138 Peptide, mHR23B Peptide, p58 Peptide, MGC107846 Peptide, zgc:65951 Peptide, RAD23 homolog B, nucleotide excision repair protein Peptide, UV excision repair protein RAD23 homolog B Peptide, RAD23 homolog B, nucleotide excision repair protein S homeolog Peptide, RAD23B Peptide, Rad23b Peptide, rd23b Peptide, rad23b Peptide, rad23b.S Peptide
- Sujet
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The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: P58, HR23B, HHR23B
Protein Size: 409 - ID gène
- 5887
- NCBI Accession
- NM_001244724, NP_001231653
- UniProt
- P54727
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