A synthetic peptide for use as a blocking control in assays to test for specificity of RLN1 antibody, Alternative Names: RLN1 control peptide, RLN1 antibody Blocking Peptide, Anti-RLN1 Blocking Peptide, relaxin 1 Blocking Peptide, H1 Blocking Peptide, RLXH1 Blocking Peptide, bA12D24.3.1 Blocking Peptide, bA12D24.3.2 Blocking Peptide, RLN1, RLN-1, RLN 1, RLN-1 Blocking Peptide, RLN 1 Blocking Peptide
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites.